Beijing, Jan 23rd (Leng Haoyang) In 2018, Spring Festival travel rush’s "ticket grabbing war" is still hot. However, for the passengers who haven’t grabbed the train tickets, they can find another way to re-plan their Spring Festival reunion. At this time, while paying attention to the "missing" of the remaining tickets, such passengers can also skillfully use air-rail combined transport, continuous transfer, network hitchhiking, reverse family visits and other measures to "curve" reunion.

　　Data Map: On January 4th, Taiyuan Railway Station, Shanxi Province, passengers bought train tickets at the manual ticketing window. China News Service reporter Wei Liang photo

　　Always pay attention to the remaining tickets and prepare for "missing"

　　For passengers who haven’t grabbed their tickets, according to the introduction of the railway department, we can pay attention to several time points when there are more refunds.

　　First, 30 minutes after the ticket is sold, if a passenger fails to pay in time after successfully grabbing the ticket, these ticket sources will return to the ticket warehouse after 30 minutes;

　　Second, on the 15th day before driving, according to the relevant regulations on railway refund, refund fees are not charged for those who refund tickets more than 15 days before driving, and passengers with uncertain trips often choose this time node to apply for refund.

　　The third is one to two days before driving. At this time, passengers who occupy tickets can basically determine the itinerary, especially from 22: 00 to 23: 00, which is the peak time for passengers to refund their tickets;

　　Fourth, before driving, the system will release some of the remaining tickets, and passengers who have not grabbed the tickets can "catch up" at this time.

　　In addition, the reporter noticed that some trains temporarily stopped selling tickets due to map adjustment, and some temporary passenger trains were added by the railway department. Passengers who did not grab tickets can pay more attention to the ticketing time of such trains in order to grab tickets at the first time.

　　Clever use of air-rail combined transport can "curve home"

　　In Spring Festival travel rush, long-distance train tickets are generally "one ticket is hard to find". In this regard, passengers can re-plan the route, air-rail combined transport, and curve home.

　　Nowadays, many airlines and railway departments have launched air-rail combined transport, flying to cities near their destinations first, and then transferring to high-speed trains to go home, or taking a high-speed train first, and then transferring to planes to fly to their destinations.

　　As for the cost, compared with the railway and Spring Festival travel rush, there will be some situations in air transportation where the capacity of some routes is relatively sufficient and the discount is large. Choosing air-rail combined transport is not only easy to buy tickets but also affordable.

　　Taking Beijing to Ningbo as an example, the reporter’s inquiry showed that on February 14th (the 29th day of the twelfth lunar month), not only was it hard to get a train ticket, but it also cost more than 1,000 yuan to fly. If you fly to Shanghai first on February 14th, the cheapest air ticket is only 400 yuan, and then transfer to a high-speed train with a price of 100 yuan, the whole journey will only take you around 600 yuan, which not only reduces the difficulty of purchasing tickets, but also makes it more cost-effective.

　　Try "connecting and transferring" and buy more stops.

　　The recommendation of the "continuous transfer" scheme introduced by the railway department last year can also reduce the difficulty for passengers to purchase tickets. When passengers can’t buy through tickets, they can choose the "continuous transfer" function, and the ticketing system will show passengers the remaining tickets of some trains that transfer once on the way. If passengers choose to buy, they can complete the payment of tickets for two trips at one time.

　　The reporter inquired about the train ticket from Beijing to Lanzhou on February 14 at the 12306 client, and found that there were only 8 trains a day on this line, and there were no tickets left. The reporter also inquired about the tickets from Beijing to Xi ‘an on the same day, and found that among the 32 trains, some high-speed trains still have tickets available for purchase.

　　The reporter also inquired about the tickets from Xi ‘an to Lanzhou, and found that there were 76 trains on February 14th, and there were still many tickets left. If you transfer home in this way, it will make it easier for passengers to buy tickets.

　　In addition, passengers can also try to buy more stops. According to the principle of "ensuring long distance" of the railway department, passengers can try to buy a few stops backwards when purchasing tickets, and get off early, or try to buy tickets from the previous stops to increase the chances of buying their favorite tickets.

　　You can choose a long-distance "ride" and pay attention to safety.

　　In recent years, the rise of long-distance "hitchhiking" has also greatly facilitated passengers’ way home during the Spring Festival.

　　Zhang Peng works in Beijing and lives in Jiyuan, Henan. Zhang Peng said that although the distance is not far, there is no direct high-speed train, and there are only five trains a day, which takes about 10 hours. If you choose to take the high-speed train to Zhengzhou and then transfer, on the one hand, it is not easy to buy tickets, on the other hand, it is more troublesome.

　　Zhang Peng told the reporter of Zhongxin. com that he has been a frequent visitor to the long-distance ride. He used the ride to return home during the 11th holiday last year, and he still plans to take the ride this Spring Festival. Although the fare of more than 300 yuan is twice as high as 178 yuan for a hard sleeper, it is convenient and worry-free.

　　On the client side of a network car, just select the "cross-city" option in the "Ride" interface, then enter the departure time, departure place and destination to get a car, and you can also see the estimated price. From Fuchengmen, Beijing to Jiyuan Bus Station, the estimated cost is 341.8 yuan.

　　The safety of the network car has also been concerned. In this regard, the police reminded that when taking a car online, it is best to write down the license plate number before getting on the bus. It is best not to carpool with people you don’t know and share your position with relatives and friends at any time. In case of danger, you should keep calm and call the police in time.

　　"reverse visiting relatives" to realize another kind of reunion

　　Wang Bo, a native of Harbin, has worked in Beijing for three years. In the previous two years, he was a member of Spring Festival travel rush’s "ticket grabbing army", but he plans to invite his parents to Beijing for the New Year this year.

　　Wang Bo told the reporter of Zhongxin. com that going home every year is very "heart-tired". Tickets are too difficult to grab, and it is inevitable to visit relatives and friends when going home. It has become a luxury to take advantage of the Spring Festival holiday to have a good rest.

　　"My father has always wanted to come to the National Centre for the Performing Arts to watch a performance, just taking advantage of the Spring Festival to take his parents around Beijing. During the Spring Festival, there are fewer Beijingers, and a family of three can have a good year in Beijing quietly." Wang Bo said.

　　In this regard, the reporter inquired about the train ticket from Beijing to Harbin on February 14 and found that "one ticket is hard to find", and even the economy class of the plane is not much left. However, if there is a "reverse reunion", the ticket source from Harbin to Beijing is sufficient, and the minimum flight cost is only 200 yuan. (End)

　　On December 26th, the 24th meeting of the 13th the National People’s Congress Standing Committee (NPCSC) deliberated and adopted the 11th Amendment to the Criminal Law (hereinafter referred to as the Amendment), which will be officially implemented on March 1st, 2021.

　　Looking at this amendment, it involves five major points of the capital market: 1. For fraudulent issuance, the amendment raises the maximum term of imprisonment from 5 years to 15 years, and changes the fine for individuals from 1%~5% of illegally raised funds to "concurrently fine", cancels the upper limit of 5%, and increases the fine for units from 1%~5% of illegally raised funds to 20%~1 times.

　　 2. For information disclosure fraud, the amendment will increase the maximum sentence of the relevant responsible personnel from 3 years to 10 years, and the fine amount will be changed from 20,000 yuan to 200,000 yuan to "fine concurrently", and the upper limit of 200,000 yuan will be cancelled.

　　 3. Strengthen the criminal accountability of "key minority". Incorporate the controlling shareholder and actual controller into the scope of criminal law regulation, such as organizing, instigating fraudulent issuance, making false information disclosure, and concealing relevant matters by controlling shareholder and actual controller, which leads to the disclosure of false information by the company.

　　 4. Compacting the "gatekeeper" responsibilities of intermediaries such as sponsors. The sponsor is regarded as the subject of the crime of providing false documents and the crime of issuing documents with great inaccuracy, and the criminal responsibility shall be investigated for this crime.

　　 5. With reference to the provisions of the new securities law, in view of the new manipulation situation in the market, it is further clear that criminal responsibility shall be investigated for new market manipulation behaviors such as "fraudulent transaction manipulation", "confusing transaction manipulation" and "hat grabbing manipulation".

　　The CSRC pointed out that this revision of the criminal law is another major legislative activity involving the capital market after the completion of the revision of the securities law, which shows the firm determination of the state to "zero tolerance" against securities and futures crimes, and has far-reaching significance for effectively raising the illegal cost of securities, protecting the legitimate rights and interests of investors, maintaining market order, promoting the reform of the registration system, and ensuring the stable and healthy development of the capital market.

　　Greatly improve the criminal punishment of securities and futures crimes.

　　 According to the CSRC, the revision of the criminal law adheres to the problem orientation, highlights key points, and aims at preventing and resolving financial risks, ensuring financial reform and maintaining financial order. It is compatible with the reform of the registration system with information disclosure as the core and is linked with the revision of the securities law, which greatly improves the criminal punishment for four types of securities and futures crimes, such as fraudulent issuance, false information disclosure, false certification documents provided by intermediaries and market manipulation. To create a standardized, transparent, open, dynamic and resilient capital,

　　Greatly increase the penalties for crimes such as fraudulent issuance and information disclosure fraud.Illegal and criminal acts such as fraudulent issuance and information disclosure fraud are the "cancer" of the capital market, and the amendment has greatly strengthened the criminal crackdown on the above crimes. For fraudulent issuance, the amendment will raise the upper limit of imprisonment from 5 years to 15 years, and modify the fine for individuals from 1%~5% of illegally raised funds to "concurrently fine", cancel the upper limit of 5%, and increase the fine for units from 1%~5% of illegally raised funds to 20%~1 times. For information disclosure fraud, the amendment will increase the maximum sentence of the relevant responsible personnel from 3 years to 10 years, and the fine amount will be changed from 20,000 yuan to 200,000 yuan to "combined fine", and the upper limit of 200,000 yuan will be cancelled.

　　Strengthen the investigation of criminal responsibility of "key minorities" such as controlling shareholders and actual controllers.In practice, controlling shareholders and actual controllers often play an important role in cases such as fraudulent issuance and information disclosure fraud. The amendment strengthens the accountability of such subjects, and clearly includes the behaviors of controlling shareholders and actual controllers, such as organizing and instigating fraudulent issuance, making false information disclosure, and concealing relevant matters by controlling shareholders and actual controllers, which leads to the disclosure of false information by the company, into the scope of criminal law regulation.

　　Compacting the "gatekeeper" duties of intermediaries such as sponsors.Intermediaries such as sponsors are the "gatekeepers" of the capital market, and their diligence is very important for the healthy development of the capital market. The amendment clearly regards the sponsor as the subject of the crime of providing false documents and the crime of issuing documents that are grossly inaccurate, and applies this crime to investigate criminal responsibility. At the same time, for lawyers, accountants and other intermediaries who produce false documents in securities issuance and major asset trading activities, if the circumstances are particularly serious, a higher sentence is clearly applicable, and the maximum sentence can be 10 years in prison.

　　Maintain effective connection with the revision of the securities law.On the one hand, depository receipts and other securities legally recognized in the State Council are included in the scope of regulation of fraudulent issuance crimes, providing sufficient legal basis for cracking down on fraudulent issuance of depository receipts and other securities in the future; On the other hand, with reference to the provisions of the new securities law, in view of the new manipulation situation in the market, it is further clear that criminal responsibility should be investigated for new market manipulation behaviors such as "fraudulent transaction manipulation", "confusing transaction manipulation" and "hat-grabbing manipulation".

　　We will speed up the revision and improvement of criminal filing and prosecution standards.

　　Regarding the follow-up work of the amendment, the CSRC indicated that in the next step, it will take the opportunity of earnestly implementing Amendment 11 of the Criminal Law as an opportunity to accelerate the revision and improvement of the standards for criminal filing and prosecution, strengthen the publicity and education on the content of Amendment 11 of the Criminal Law, continuously deepen the cooperation with the judicial organs, adhere to the "zero tolerance" to crack down on various securities and futures crimes such as fraudulent issuance and information disclosure, effectively raise illegal costs, effectively protect the legitimate rights and interests of investors, and fully guarantee them.

　

　　Source: Issued by China Securities Regulatory Commission, Securities Times Network

　　Press conference site

　　CCTV News:On October 13th, the State Council held a press conference on import and export in the first three quarters. In response to a reporter’s question, Li Kuiwen, spokesman of the General Administration of Customs and director of the Statistics and Analysis Department, introduced that the Customs resolutely implemented the decision-making arrangements of the CPC Central Committee and the State Council, concentrated on "six stables" and "six guarantees", made overall plans to prevent and control the epidemic situation at ports and promote the steady growth of foreign trade, further proposed 56 measures to stabilize foreign trade and foreign investment, and continuously improved the level of customs clearance facilitation.

　　First, reform and innovation promote trade facilitation.We will comprehensively promote facilitation measures such as "two-step declaration", "declare in advance", "green channel" and exemption from on-site inspection to improve customs clearance efficiency. In September, the overall customs clearance time for imports and exports in China was 35.02 hours and 1.86 hours respectively, which was 64.04% and 84.87% lower than that in 2017, both of which have decreased for five consecutive months.

　　The second is to find ways to reduce the cost of enterprises.By reducing and exempting the import delay payment, late payment fee and the interest of deferred tax on domestic sales of processing trade goods, the company has reduced and saved nearly 200 million yuan. Especially among the import and export enterprises that use tariff guarantee insurance, SMEs account for about 70%.

　　The third is to accelerate the pilot to promote the development of new formats.Comprehensively promote the regulatory measures for the return of cross-border e-commerce export commodities, and carry out pilot projects for cross-border e-commerce enterprises to export to enterprises. Encourage the central and western regions, the northeast and other places to carry out market procurement trade pilot. In the first three quarters, the import and export through the customs cross-border e-commerce management platform was 187.39 billion yuan, up 52.8%, and the market procurement export was 509.86 billion yuan, up 35.5%.

　　The fourth is to take multiple measures to promote the creation of a new highland for opening up.Vigorously support the construction of Hainan Free Trade Port and Yangshan Comprehensive Bonded Zone, intensify the innovation and replication of customs supervision system in the Pilot Free Trade Zone, and promote the full implementation of global maintenance and remanufacturing business in the comprehensive bonded zone. In the first three quarters, the import and export of the national comprehensive bonded zone was 2.34 trillion yuan, an increase of 15.1%, 14.4 percentage points higher than the growth rate of foreign trade.

　　The fifth is to fully guarantee the import of key products.We will continue to expand the scope of importing countries and commodities, newly approve 5,965 foreign registered enterprises, and increase the import security of important agricultural products and foods such as meat, grain, aquatic products and fruits. In the first three quarters, meat and grain were imported 162.65 billion yuan and 253.36 billion yuan respectively, up by 87.3% and 20.7% respectively.

　　In the next step, the national customs will deepen reform and innovation, do a good job in the work of "six stabilities" and "six guarantees", fully promote the implementation of 56 measures to further stabilize foreign trade and foreign investment, promote the stable development and quality improvement of foreign trade, and make positive contributions to promoting the formation of a new development pattern.

　　According to The New York Times’s report on July 13th, SAG-AFTRA announced that it had failed to reach a new agreement with AMPTP, which represents the interests of film and television production companies, and decided to strike.

　　Earlier, the American Writers’ Union (WGA) began a strike on May 2. SAG-AFTRA will soon join their camp, which is also after 1960, when actors and screenwriters went on strike again. During the strike, the actors’ union will stop all script, film and TV production under AMPTP.

　　Last month, members of the Actors’ Union voted overwhelmingly by 98%, authorizing the union management to go on strike if no agreement can be reached in the negotiations, and at the same time authorizing the union leaders to "stick it out" in the negotiations with the management.

　　In the latest statement, the Actors’ Union said: "SAG-AFTRA is eager to reach an agreement that fully meets the needs of performers, and the producer’s response to the most important proposal of the Actors’ Union is to insult and disrespect our contribution to this industry. These companies refuse to make meaningful contacts on some topics, while others completely hinder us. "

　　The union also said that after more than four weeks of negotiations, AMPTP is still unwilling to provide a fair deal on key issues that are crucial to the members of the Actors Union. "

　　AMPTP represents Amazon, Apple, Disney, Comcast’s NBC Universal, Netflix, Paramount Universal, Sony and Warner Bros. Discovery and other major film companies and streaming media companies.

　　It is reported that the demands of the actors’ union include "economic fairness, late dividends, standardizing the use of AI, and alleviating the burden of self-recorded audition fees in the whole industry".

　　The core issue is salary and the use of artificial intelligence.

　　The actors’ union believes that the remuneration of actors has "seriously shrunk" in recent years. Under the old system, if a TV series is a great success, actors can expect that there will be a large amount of checks left in their bank accounts in the next few years. Actors believe that in the era of streaming media, cakes become smaller and checks become smaller.

　　"Fundamentally, we are interested in ensuring that our members share the success of the projects they create." Duncan Crabtree-Ireland, the chief negotiator of the trade union, pointed out.

　　Actors are also very concerned about artificial intelligence and how to use this technology to replicate their previous performances without paying or consulting them.

　　The strike of the actors’ union means that almost all American TV dramas and movies being filmed will stop shooting. During the strike, hundreds of thousands of actors who joined the trade union were not allowed to shoot any films and TV works, and could not attend any press conference or film premiere.

　　21st century business herald reporter Ji Yuanyuan reports from Shanghai Recently, Yixinhe Pharmaceutical Technology Co., Ltd. (hereinafter referred to as "Yixinhe Medicine") developed and produced, and (1) Shakuba Quvalsartan Sodium Tablets (brand name: Yixintan) which was exclusively commercialized was approved by National Medical Products Administration (NMPA). Yixintan is the first generic drug of shakubatravalsartan sodium tablets approved for marketing in the global regulatory market by breaking through the original research patent through innovative crystal forms. The approved indications of this product are for treating essential hypertension and adult patients with chronic heart failure (NYHA II-IV grade, LVEF≤40%) with reduced ejection fraction, so as to reduce the risk of cardiovascular death and hospitalization for heart failure.

　　Immediately afterwards, Unacon also announced that its subsidiary company Shiyao Ouyi developed Shakubatrivalsartan sodium tablets (50mg, 100mg, 200mg) which have obtained the drug registration approval issued by National Medical Products Administration, and regarded them as the adult patients with chronic heart failure (NYHA II-IV grade, LVEF≤40%) with reduced ejection fraction, which reduced the risk of cardiovascular death and hospitalization for heart failure.

　　With the approval of domestic shakubatravalsartan sodium tablets, Novartis, the original drug manufacturer, also released information at the first time, saying that the marketing license for the generic drug of Novartis’ original research product shakubatravalsartan sodium tablets was approved, and Novartis declared that the pharmaceutical active ingredient of the original research product Noxintuo was protected by patents ZL200680001733.0 and ZL201210191052.2 in China.

　　According to the relevant provisions of Article 11 of China’s Patent Law, any enterprise or individual shall not manufacture, use, promise to sell (including applying for online registration, participating in bidding, etc.), sell or import products falling within the scope of the above patent protection before the expiration of the above patent period, otherwise it will constitute patent infringement. To this end, Novartis emphasizes that it will reserve the right to claim its patent right against infringing imitations from relevant judicial and/or administrative organs.

　　Regarding the patent issue, according to the public information, in April 2017, the patent of Shakubatroxobin Sodium Tablets registered by Novartis was declared invalid in China. On July 2, 2021, the crystal patent was also partially invalidated in China. Yixin and Medicine also emphasized in the official disclosure information that in 2022, the domestic sales of Shakuba Quvalsartan sodium tablets totaled nearly 3 billion yuan, and its China patent will expire in November 2026. Yixintan is a first-line drug for the treatment of heart failure and hypertension with independent intellectual property rights, which can legally make the majority of patients with heart failure and hypertension in China use equivalent and affordable innovative drugs three years in advance.

　　It can also be seen that the domestic Shakubatroxobin Valsartan sodium tablets have been approved one after another, which will bring certain market challenges to the original drug.

　　More than 10 pharmaceutical companies compete for the market

　　Shakubatroxobin and valsartan sodium tablets are a new type of eutectic drug composed of enkephalinase inhibitors Shakubatroxobin and angiotensin receptor blocker valsartan sodium tablets in a molar ratio of 1:1. Eutectic structure can make the absorption and elimination rates of shakubarb and valsartan sodium tablets similar, and ensure the synchronous consistency of their efficacy. In addition, compared with independent preparations, eutectic drugs have the advantages of constant composition ratio, good storage stability, and can significantly improve drug solubility and oral bioavailability.

　　As a representative drug of ARNi, Shakubatroxobin sodium tablets have been unanimously recommended by domestic and foreign guidelines in recent years. In 2021, the American Heart Association proposed that ARNi drugs should be given priority to patients with HErEF, and it is recommended to use them to the maximum tolerated dose or target dose (Class I). In 2018, China Heart Failure and Treatment Guidelines also recommended to replace ACEI/ARB with ARNi to further reduce the incidence and mortality of heart failure (Class I).

　　Sakubatravalsartan sodium was originally researched by Novartis Entresto, and was first approved by the FDA in July 2015. It is the world’s first breakthrough and innovative drug in the field of heart failure treatment, and was approved to enter the domestic market for the first time in July 2017. It was included in the national medical insurance category B catalogue through negotiation in 2019, successfully renewed in 2021, and added indications for essential hypertension. In 2021, the global sales of the original research sand kubatroxobin sodium reached US$ 3.548 billion. In 2022, its global sales scale reached US$ 4.644 billion, up 37% year-on-year. In the first half of 2023, the drug also grew into the best-selling drug of Novartis, with sales reaching US$ 2.915 billion, up 31% year-on-year, and it is expected to exceed US$ 6 billion in the whole year.

　　In the China market, the original yanshakubatravalsartan sodium is also a heavy variety. According to the data of the Minenet, the sales growth rate of this product in China’s three major terminals and six major markets has reached triple digits in recent years. In 2021, it exceeded 2 billion yuan for the first time, up 127.62% year-on-year, with full market potential; In 2022, the sales of Shakubatroxobin Sodium Tablets in China’s three major terminals and six major markets exceeded 2 billion yuan. Among them, the hospital market (public hospital terminal+public primary medical terminal) is the main sales channel, with a year-on-year increase of 6.54%.

　　In this regard, some brokerage analysts told 21st century business herald that the innovative product layout must be aimed at chronic diseases, major diseases, diseases that pose a major threat to people’s health, such as cardiovascular diseases, tumors and major infectious diseases. At the same time, the core of making medicine is clinical value. With the rapid development of life science, many interdisciplinary fields are very active, and the large-scale treatment methods focusing on large populations are worthy of attention.

　　"The successive approval of domestic shakubatravalsartan sodium tablets is a great benefit for cardiovascular patients, although the layout of many domestic pharmaceutical companies is already in the clinical stage, except for the single-minded and pharmaceutical/Fosun Pharma, Shiyan Ouyi, including Sichuan Kelun, Chengdu Beite, Qilu Pharmaceutical, Zhengda Tianqing, etc. are also accelerating the layout. This is due to the accelerated layout of many domestic pharmaceutical companies, and the prices of related products are expected to be further lowered, eventually benefiting more patients. " The above analyst said.

　　According to the data of Minenet, at present, there are three companies that have production approval documents for Shakuba Quvalsartan Sodium Tablets. Among them, Unacon Ouyi Pharmaceutical Co., Ltd. and Nanjing Yixin and Medical Science and Technology Co., Ltd. were all approved on the same day with four types of imitation, which are regarded as over-evaluation, and tied for the first imitation and the first over-evaluation. In addition, 17 enterprises, including Shandong New Times Pharmaceutical, Nanjing Zhengda Tianqing Pharmaceutical and Qilu Pharmaceutical (Hainan), all reported their production under the new classification.

　　An unavoidable patent dispute

　　The competitive anxiety between Chinese and foreign pharmaceutical companies in Shakuba Quvalsartan sodium tablets is also considered to be an important reason for patent confrontation. At the same time, in recent years, patent disputes between original drugs and generic drugs have occurred from time to time. 21st century business herald reporter found through the search of Wisdom Bud database that as of the latest, there are more than 700 drug patents with litigation results in China, and more than 99% of them are invention patents. It can be seen that the handling of drug patent disputes needs urgent attention.

　　Yixinhe Medicine also emphasized in the official information disclosure that Yixintan is a first-line drug for the treatment of heart failure and hypertension with independent intellectual property rights. Compared with the reference crystal form, when the relative humidity changes from 20% to 60%, it absorbs less water and is more stable, and can be sealed and stored below 30℃. This stable crystal form is more suitable for the vast China market.

　　When talking about patents, some pharmaceutical executives also told 21st century business herald that the research and development of original innovative drugs has always been a "three high" industry with high threshold, high risk and high return. According to the latest literature, it takes an average of 12.5 years for a new drug to go on the market, which costs nearly $2.6 billion, and the success rate is less than 10%. Every new drug project is the most important decision of an enterprise, and the project process needs a lot of data research, especially the research on patents, documents and regulations takes a lot of time.

　　"Therefore, how to find a balance between ensuring the innovation enthusiasm of the original drug research enterprises and reducing the burden on patients has been hotly debated. The FDA’s definition of generic drugs is very strict, and the requirements must be consistent with the dosage form, specifications and administration route of the copied products. If it is inconsistent, it will be declared as a new drug. " The above-mentioned pharmaceutical company executives said that for the long-term public interest, the state needs to protect the enthusiasm of the original drug research and development enterprises. At the same time, in order to limit the original drug research and development enterprises, it is necessary to encourage the imitation research and development of the original drug from the level of institutional norms and ensure the interests of generic drug enterprises.

　　In order to better balance the interests of the original research drug and generic drug companies with the system, the new Patent Law, which came into effect on June 1, 2021, established the drug patent linking system in China, aiming at linking the two legal procedures, so as to clarify the interest relationship between the original research drug manufacturers and generic drug manufacturers and avoid the problem of patent punishment when the generic drug research and development is completed.

　　As for how enterprises can avoid patent risks, Hou Xuchao, the founding partner of CIC Consulting, also told 21st century business herald that from the perspective of investment and financing, pharmaceutical companies have five key parameters when choosing product pipelines, including the success rate of products under research, patient base, product penetration rate, product pricing and patent life. With the improvement of pharmaceutical companies’ R&D strength, patent life needs more and more attention.

　　"For the patent situation of unlisted drugs, investors need to hire professional IP lawyers to conduct detailed investigations. Because patent conflicts will directly make it difficult for candidate drugs to be marketed, and even directly affect the product value measured by all the above parameters, it is an essential step for patent investigation. " Hou xuchao said.

　　There is a huge crowd in the chronic disease market behind Shakuba Quvalsartan sodium tablets. In terms of hypertension alone, China, as a big country with hypertension, has 245 million adult hypertensive patients, which means that Shakuba Quvalsartan sodium tablets have a broad market space and are an important direction for the future development of drugs. I believe many domestic and foreign manufacturers will make layouts and list related products one after another.

　　However, it should also be noted that after the appearance of the first imitation drug, the clinical data, approval time and product price of the follow-up drugs and enterprises will all be factors affecting the competition pattern, especially the clinical effectiveness and safety, which will be the key to decide who can go further in this track.

　　CCTV News:Today, the China Meteorological Bureau held a consultation meeting with various departments on the weather during the Spring Festival holiday. According to the forecast, during the holiday, the temperature in most parts of the north was low, while the temperature in the south was high and rainy. From New Year’s Eve to the second day, the weather in most parts of the country is generally conducive to travel. From the third day, affected by strong cold air, there will be a large range of rain, snow and strong winds in the central and eastern regions.

　　According to the forecast, from the 4th night today, due to the influence of a medium-intensity cold air, there will be 4 to 6 northerly winds from north to south in the central part of northwest China, central and eastern Inner Mongolia, most of the northeast, Jianghuai, Jiangnan and eastern Guizhou. The temperature will drop by 4 ~ 8℃, and the local temperature will drop above 12℃. Everyone should pay attention to wind protection and warmth when traveling.

　　From New Year’s Eve to the first day, there is no obvious cooling and snowfall in most parts of the country, which is conducive to travel. Around the second day of junior high school, a strong cold air will affect northern Xinjiang, bringing strong winds, strong cooling and snowfall. From the third day to the fifth day, this cold air will continue to move eastward and affect the central and eastern regions, bringing northerly winds of 4 ~ 6 grades, and the temperature will also drop by 6 ~ 10 C. Among them, the local cooling in central and southern Hunan and southeastern Guizhou will exceed 14 C. At the same time, there is snow or sleet weather in the eastern part of northwest China, north China, south-central part of northeast China, Huanghuai, Jianghuai and Jianghan. From the fifth day to the sixth day, there are northerly winds with 6-8 grades and gusts of 9-10 grades in Bohai Sea, Yellow Sea, East China Sea, Taiwan Province Strait, northern South China Sea and Beibu Gulf.

　　During the Spring Festival holiday, there will be rainy weather in the south. It is expected that there will be more light rain or showers in Jiangnan, northern South China and eastern Guizhou, and the number of rainy days will be 4-6 days.

　　In addition, it should be noted that there will be heavy fog in Qiongzhou Strait on New Year’s Eve and the early morning of the first day, and the local visibility will be less than 500 meters. On the second day, there are heavy fog in Sichuan Basin, Henan, Shandong, Jiangsu, Anhui, Hubei and other places, and there are strong fog in some areas, so it is necessary to guard against the adverse effects of low visibility on travel. (CCTV reporter Ren Meimei)

11,000 escalators were checked 10 days ago, and an elevator "swallowing people" incident occurred in Hubei, which caused strong concern about elevator safety. The executive meeting of the municipal government held yesterday studied and deployed matters on strengthening elevator safety supervision. At the subsequent press conference, Yao Jianming, director of the Municipal Bureau of Quality and Technical Supervision, revealed the specific addresses of 19 "Suzhou Shenlong" escalators in the city, and said that these 19 escalators could not be put into use again until there were no safety hazards. The city is also investigating 11,000 escalators, which is expected to be completed before August 10th. Latest progress: 6,250 escalators have been investigated. After the "July 26th" escalator accident in Jingzhou, Hubei Province, the Municipal Quality Supervision Bureau organized a special investigation and found that there were 19 escalators in Guangzhou, all of which were located in shopping malls and supermarkets, including 8 in Tianhe, 5 in Huadu, 2 in Haizhu, 1 in Baiyun, Panyu, Yuexiu and Huangpu, and 6 in the same model as the accident. The eight "Suzhou Shenlong" escalators located in Tianhe are all located in the Gaodehui Olympic Sports Center in Dongpu; In addition, CR Vanguard, Minrun Supermarket and Huadu Xinhua Department Store are all involved. Yao Jianming said that all the 19 sets of "Suzhou Shenlong" have been ordered to stop using. At present, the preliminary investigation has been completed, and no similar hidden danger of cover overturning has been found. It is asking its manufacturing unit "Suzhou Shenlong" Elevator Company to further confirm this and make sure that there are no safety hazards before it can be put into use again. It is reported that there are 114,000 elevators in Guangzhou, including about 11,000 escalators.And the annual growth rate is about 10%, the number is second only to Beijing, Shanghai and Shenzhen, ranking fourth in major cities in China. Yao Jianming revealed that a comprehensive inspection of 11,000 escalators in the city is being organized. Maintenance units and users have inspected the cover plates and connecting plates of escalators one by one. At present, 6,250 escalators have been inspected, and it is expected that the inspection of 11,000 escalators in the city will be completed before August 10. In addition, the corresponding escalator cover plate and protective baffle are added to the supervision and spot check task of escalator. Focus question: Has the escalator been inspected? There is a green inspection sign. Since all the escalators in the city are undergoing safety inspection, how can ordinary citizens know whether the elevators around them have been inspected and qualified? Yao Jianming said: "Every inspection is recorded and prompted. According to the regulations, it will be inspected once every 15 days, and a sign of inspection will be posted in the elevator." Yang Yanhui, director of the special equipment safety supervision department of the Municipal Quality Supervision Bureau, added that if you find that there is no green sign that has passed the statutory inspection in the elevator, you can call 96333 or 12365 to make a complaint. Yao Jianming also said that there are about 13,000 elevator maintenance personnel in Guangzhou, which can basically meet the needs. Regular maintenance and maintenance system is implemented for elevator maintenance enterprises, and licensing system is implemented for maintenance enterprises. The staff of maintenance enterprises, that is, technicians, should also be employed on the basis of qualifications. At present, 260 maintenance enterprises are performing their duties.Of course, the mobility of maintenance personnel is still relatively large because of the treatment. Next, we will strengthen supervision and strengthen the training of technicians in maintenance enterprises. He also revealed that the maintenance companies have signed contracts with the elevator users. If citizens find that there is a problem with the elevator, they can call 96333 to tell the monitoring center or complain to the users. Who is responsible for the problem? In fact, elevator accidents often happen. Statistics show that in the first half of this year, Guangzhou handled 2,173 elevator-trapped people and 1,341 elevator failures, and rescued 6,289 trapped people. The average time for rescuers to arrive at the scene was 14.4 minutes, 52% less than the national legal time. In the first half of 2015, there were 1.14 people trapped every 10,000 elevators every day, a year-on-year decrease of 25.97%. Then, who is responsible for the elevator accident? Yao Jianming said that it is necessary to implement the first responsibility and complete the elevator confirmation. It is an important prerequisite for the reform of elevator safety supervision to clarify the responsibility of the elevator user and clearly define the relationship between power and responsibility of each subject in each link. Elevator confirmation effectively solves the complex relationship among elevator owners, users and managers, and firmly locks the first responsible person for elevator safety. No confirmation, no use. The confirmation rate of Guangzhou elevator is 100%. Yang Yanhui, director of the Special Equipment Safety Supervision Department of the Municipal Quality Supervision Bureau, explained: "The Guangdong Province Elevator Safety Regulations, which will be implemented on October 1 this year, has the concept of a user manager, just like buying a car.This car is in your name, and if there is an accident, you will bear the responsibility. It is reported that the user manager mainly has 13 responsibilities, including daily supervision, maintenance, and first assuming the liability for compensation. How to repair hidden dangers? I hope to use the property maintenance fund. In practice, when some real estate elevators have problems and apply for property maintenance funds for maintenance, they encounter many difficulties, resulting in long-term shelving of elevators. How to solve this problem? It is reported that Guangzhou is establishing a system of elevator maintenance and use of public funds for housing maintenance to facilitate the use of funds. The newly revised "Guangzhou Property Special Maintenance Fund Management Measures" regards serious hidden dangers such as elevator rushing to the top and squatting at the bottom, and situations that the quality supervision department thinks need maintenance as emergencies that can directly use funds, creating convenient channels for the maintenance and use of funds. It is reported that the method has been completed for comments, but the official manuscript has not yet been issued. Yang Yanhui said: "The problem of elevator maintenance funds has really been bothering us. There are so many elevator problems in the market, some complaints have been dealt with, but they will not work in a few days. We sum up this phenomenon as psoriasis of elevator complaints. Some elevators need to be replaced. Where does the money come from? Take it from the housing maintenance fund, but some communities don’t have property maintenance funds. They only raise money from house to house, but many people don’t pay it, which affects the normal use of elevators. "

　　All-Media Reporter Du Yang of Rule of Law Daily

　　In 2020, a residential property management company in Beijing sued Gu, the owner of the residential area, to the court, demanding that Gu pay more than 90,000 yuan of property service fees and late fees from 2016 to 2019. During the trial, Song Tong, Gu’s attorney and executive director of Beijing Songtong Law Firm, combined with the evidence, proposed that the property service actually provided by the property company to Gu was lower than the standard agreed in the contract, and advocated reducing the property service fee. In addition, because the property company did not provide services as agreed in the contract, Gu did not maliciously default on the property fee, so there is no need to pay the late payment fee. In the end, the court decided to reduce the cost of a property service of more than 10 thousand yuan, and there is no need to pay late fees.

　　At present, the masses have put forward higher demands and more expectations for property services, owners’ awareness of safeguarding rights according to law has been continuously enhanced, and disputes concerning the right to know and the price adjustment of property services have emerged constantly, showing a diversified and new trend.

　　"Lawyers’ participation in solving property service disputes can not only promote rational communication between the parties and the court, but also promote the functional integration of mediation and adjudication, realize the diversion of cases in litigation procedures, effectively save judicial resources, and effectively resolve property service disputes at the source." Liu Jingkun, a professor at China University of Political Science and Law, told the reporter of Rule of Law Daily.

　　With a clear legal basi

　　Are the problems such as the occupation of residential green space and the illegal construction by owners belonging to the category of property management? What is the boundary of management? Hong Bijing, a lawyer of Fujian Sanshan Law Firm, told the reporter that the above problems were controversial in the past, and now lawyers can directly solve the disputes according to the management obligations of property service enterprises stipulated in Article 942 of the Civil Code.

　　Bao Hua, a lawyer of Beijing Hairun Tianrui Law Firm, believes that there are many levels of legislation and a long time span in the field of property management. When lawyers intervene in related cases, they need to fully understand the legislative background and legislative purpose to carry out legal services.

　　In recent years, at the national and local levels, many "good laws" related to property management have been promulgated one after another, further clarifying the rights and obligations between owners and property service enterprises and optimizing the "weapons" for lawyers to maintain fairness and justice.

　　"For the first time, the Civil Code included the’ property service contract’ as a typical contract, and stipulated the conclusion, dissolution, termination and continued performance of the contract, which made up for some omissions in the past and played an important role in clarifying the boundaries of powers and responsibilities for all parties." Bao Hua said.

　　Hong Bijing told reporters that with the publication of normative legal documents such as "Interpretation of the Supreme People’s Court on Several Issues Concerning the Application of Laws in the Trial of Property Service Disputes", lawyers have a clearer legal basis when they participate in mediation of property service disputes.

　　Effectively promote source dispute resolution

　　"I don’t live in this house, why should I pay the property fee?" In December 2021, Yang, from Nanyu Town, Minhou County, Fujian Province, was sued by the property management company of a residential area for failing to pay the property service fee owed from March to August 2018 for a long time, and the late payment fee was more than 2,000 yuan.

　　After Hong Bijing intervened in this case, on the one hand, he suggested that Yang pay the arrears of property fees, and on the other hand, considering the defects in the selection process of the property company, he coordinated the property company to reduce some fees. After many times of communication and coordination, the two sides reached an out-of-court settlement.

　　At present, more and more lawyers are involved in the diversified mediation of property service disputes as legal experts, legal consultants and mediators, and have won the trust and recognition of the masses with their unique professional advantages and high-quality legal services, becoming a member of the social mediation pattern and playing an important role.

　　"Before the property service dispute enters the court, the establishment of a professional mediation mechanism involving lawyers can help the parties to clarify their legal responsibilities, clarify their respective rights and obligations, and promote the proper settlement of disputes." Liu Jingkun believes that for the court, with the help of the litigation source governance mechanism in which lawyers intervene in advance, the background of the case and the actual demands of the parties can be more clearly understood, and then the dispute resolution mechanisms such as mediation and adjudication can be more effectively integrated to ensure the legal and social effects of case handling.

　　"At present, all localities are using the power of lawyers to optimize the property service dispute resolution mechanism, and the role of lawyers involved in property service disputes and the ways to resolve disputes are gradually diversified." Bao Hua said that this requires lawyers not only to have a dual perspective of paying attention to the plaintiff and the defendant, but also to have the ability to clearly distinguish the boundaries of rights and responsibilities of owners, governments and managers, and to understand the practical operation in the field of property management, so as to propose a feasible mediation plan.

　　Song Tong said that while lawyers participate in resolving contradictions and disputes, they will also have more understanding and thinking about legal issues related to property service disputes, which is another virtuous circle.

　　"Lawyers are the’ regulators’ of property service disputes. Even if lawyers are involved, they may not be able to completely resolve contradictions and disputes, but in most cases, they can effectively avoid the escalation of contradictions and disputes." Hong Bijing added.

　　"Lawyers’ participation in the mediation and handling of property service disputes will help promote the establishment of a system of property management institutions." Liu Jingkun said that lawyers can give full play to their professional advantages, so that property management agencies can find the weak links in daily management in time, and then establish and improve relevant systems in a targeted manner to reduce the occurrence of property service disputes from the source.

　　Continuously improve the service level

　　"Thank you for your participation, so that the election norms of the industry committees can proceed smoothly."

　　In July 2021, the election of the owners’ committee was held in Shangjingyuan Community, Jiang Hao, Shanggan Town, Minhou County. Hong Bijing and his team of lawyers assisted as legal advisers of the town government, and they put forward perfect opinions and suggestions, which were well received by the owners.

　　In Hong Bijing’s view, lawyers can also optimize the source governance of property service disputes by helping the rule of law. "By participating in the election of the owners’ committee, providing corresponding legal advice and guidance, and promptly educating the owners about the rule of law related to property management, the fairness and justice of the election are ensured, and the rule of law literacy of the owners is also improved, so as to better prevent the occurrence of property service disputes from the source." Hong Bijing said.

　　"In the process of drafting property service contracts, formulating and implementing government policies, lawyers can play more roles and achieve better linkage with government departments and property companies." Song Tong told reporters that lawyers’ participation in the drafting of property service contracts and supervision of the performance of property service contracts will enable lawyers to have a more intuitive and comprehensive understanding when receiving feedback from the masses and achieve better solutions.

　　Bao Hua believes that the level of resolving property service disputes reflects the level of social governance to a certain extent, so lawyers should not only have legal knowledge and practical experience in property management, but also have knowledge and experience in community governance, so as to strengthen the social effect of mediating property service disputes.

　　"We should encourage and guide more lawyers to participate in the mediation of property service disputes." Liu Jingkun suggested that relevant departments should establish a special working mechanism. For common types of property service disputes, we can consider setting up a working procedure for lawyers to participate in mediation to improve the effectiveness of mediation.

Piano robot Special Olympics is playing and singing.

The painting of Microsoft robot "Xiao Bing"

"Xiao Bing" solo exhibition held in Central Academy of Fine Arts

Participants in the "to be no.1" game at the World Artificial Intelligence Conference.

The audience participated in the live interaction of Li Yuansu’s AI work "Nanjing West Road Style Migration"

　　Yangcheng Evening News reporter Jing He

　　"Humans can’t be controlled by artificial intelligence, because humans can’t create smarter creatures than humans." Ma Yun said.

　　"I disagree with you very much. We can create something smarter than human beings, but not necessarily people." Musk said.

　　On August 29th, at the opening ceremony of the 2019 World Artificial Intelligence Conference in Shanghai, Ma Yun and Tesla CEO elon musk had a tit-for-tat "quarrel".

　　Regardless of whether artificial intelligence is smarter than human beings, it is an undeniable fact that AI is infiltrating into every corner of human life, even including the field of artistic creation that was once regarded as exclusive to human beings. If the cooperation between artists and AI only creates a new means of expression, but AI itself learns to create art, which opens the door to a new world.

　　What does AI’s participation mean for creative and imaginative humanistic artistic creation? How should we define "art" today? Is it possible for everyone to become an artist in the future? Artists who are at the forefront of the trend have given us their own answers.

　　1 Smart conference live experience: somatosensory remote control and AR "crossing" are human-computer interaction.

　　Walk into the IBM exhibition area of the 2019 World Artificial Intelligence Conference and raise your hands above your head to make a gesture of love. With the countdown to 54321 over, you will successfully activate an astronaut named CIMON to "land on the moon". On the screen, the astronaut will follow some of your body movements to "swing" his body — — He is representing you "landing on the moon". You can also download photos of yourself "landing on the moon" and post them on social platforms. This CIMON is the first "AI astronaut" launched by IBM. It helped man land on the moon for the first time 40 years ago.

　　In the "to be no.1" exhibition area where Shangtang Technology cooperates with the Forbidden City, as long as you make a gesture, you can "cross" to take a photo with Confucius in ancient times, and you can also use face recognition technology to "transform" into a scholar who is in Beijing to take an exam and take an ancient imperial examination.

　　The artwork "Nanjing West Road Style Migration" created by young painter Li Yuansu using AI technology is also a popular interactive project in the exhibition hall. When the audience enters the exhibition area, the camera will capture the corresponding pictures, which are processed by human detection, background segmentation, human-computer interaction and other technologies, and then the computer will combine the study of the painter’s past works and make real-time creation. On the display screen, the audience can see their own figure and become a stylized image in real time. Although these works are only based on the creation of man-machine cooperation, it is undeniable that AI has penetrated into all aspects of human life.

　　2 Interaction triggers reverse trigger: artists begin to think about "how to express intelligent objects"

　　In fact, in the AI era, the integration of human artistic creativity and AI has become a "new trend", and there have been many interactions between them.

　　In 2017, Google launched Autodraw, a tool that can help people draw stick figures. With just a few strokes, the algorithm can identify what you want to draw and optimize it for you. In 2018, the digital creation studio OUCHHH launched an exhibition named "Poetic AI" at the Paris Art Center, France. By learning the articles of scientists who have changed human history, AI transcoded them into words and images, and then projected them into a space of 3,300 square meters through 136 projectors. The effects of light and motion are also automatically generated through preset algorithms, which can provide an immersive experience combining sound, light and shadow for the audience. Also in 2018, at Christie’s auction, the painting "The Portrait of Edmund Bellamy" created by AI was taken at a price of 432,500 US dollars (about 3.01 million yuan).

　　Interestingly, Li Yuansu pointed out a new phenomenon: artists used to like to express figures, flowers, birds and mountains. When AI appeared, some people began to think about "how to express intelligent objects". "In the past, artists may describe the sparkling water, but what excites contemporary artists may be the flashing LED lights and the computing interface of supercomputers." He believes that "these are the reverse triggers of artificial intelligence on artistic creation inspiration."

　　3 Constantly unlocking new skills: Microsoft Xiao Bing, who can write poetry and sing, also learned to draw.

　　In May 2014, Xiao Bing, an intelligent chat robot launched by Microsoft (Asia) Internet Engineering Institute, was born. This is a girl who pays attention to EQ and takes an emotional route. In the past five years, Microsoft Xiao Bing has been unlocking new skills. She published a collection of poems, learned to sing, can host programs, and learned to draw as an "supernumerary" graduate student of the Central Academy of Fine Arts. At the World Artificial Intelligence Conference, Xiao Bing’s paintings attracted many audiences with unique style.

　　The painter Xiao Bing’s debut time is not long, but he has become a minor celebrity. In May this year, Microsoft Xiao Bing, under the pseudonym of "Xia Yubing", exhibited her works for the first time at the 2019 Graduate Exhibition of Central Academy of Fine Arts, and became an "supernumerary" master graduate of Central America.

　　After graduation, Microsoft Xiao Bing is "non-stop". From June 15th to July 15th this year, the cross-border exhibition of contemporary art "Xiao Bing, Painting for a Period" was held in Liangzhu Culture and Art Center, Hangzhou, featuring paintings created exclusively by Xiao Bing and VR immersive works created interactively by new media artists Zhou Linwei and Xiao Bing. Later, Xiao Bing’s first solo exhibition "Possibility World" was held in the Art Museum of the Central Academy of Fine Arts.

　　Now just go to Xiao Bing’s homepage and enter a simple text on the page to activate her, and you can entrust Xiao Bing to make a painting for you. After extracting intention, stimulating creative inspiration, selecting content theme, trying to compose the picture, drafting line drawing modeling, painting the bottom color, deepening the picture level and polishing the details repeatedly, the painting created by Xiao Bing can be released in three minutes.

　　According to the Microsoft Xiao Bing team, Xiao Bing spent 22 months studying the paintings of 236 famous painters in the history of art. When inspired by texts or other creative sources, Xiao Bing can independently complete 100% original paintings. This originality is not only reflected in composition, but also in color, expressiveness and details. Li Di, the head of Xiao Bing’s team, stressed: "Xiao Bing’s painting ability is not based on filters and migration technology — — That is, search the picture of the corresponding theme from the landscape library, and then use the oil painting filter to process it. " He said that painting model is the third kind of AI model after text and pronunciation, and it is also the longest and hardest project.

　　Qiu Zhijie, Dean of Experimental Art College of Central Academy of Fine Arts, spoke highly of Xiao Bing’s works. "Xiao Bing’s works are diverse in style, skillful in technique, fast in painting and large in quantity, from which we can find many good paintings." Qiu Zhijie said, "We set several aesthetic rules for artificial intelligence, and it will use these rules to combine endless changes. If you set it to ‘ Do not repeat ’ The instructions, AI actually has a greater chance to get rid of the routine. "

　　Xiao Bing is developing towards the route of piano, chess, calligraphy and painting, which makes her look more like a "person". In May 2017, Xiao Bing’s original poetry collection "Sunshine Lost Glass Window" was published, which is the first poetry collection created entirely by AI in human history. This year, Xiao Bing and the poet’s poetry collection "Flowers are Silence of Green Water" came out, which is also the result of writing poems jointly by man and machine. About 200 poems were finally selected from 6,000 submissions.

　　However, whether it is poetry or painting, Xiao Bing’s works still clearly bear traces of AI. For example, there is a lack of effective transition between poetic images, irrationality between logics, and inconspicuous poetry, etc. Although Xiao Bing’s team said that Xiao Bing’s paintings are close to human level, the audience can still see with the naked eye that Xiao Bing’s works have no three-dimensional sense of oil painting, appear more flat, and can’t see the lines of a painting.

　　4 human beings are hard to be replaced: AI singers who lack emotion are hard to impress people.

　　On the evening of August 29th, when the virtual singer Tianyi Luo’s singing sounded in the Shanghai Benz Cultural Center, the familiar Jasmine seems to be a little strange. As the most famous virtual singer in China, Tianyi Luo has held ten thousand people’s holographic concerts for three years in a row, creating a precedent of "domestic virtual singer AR live broadcast on a large variety show".

　　Then came the piano robot Special Olympics from Italy. I saw his 53 fingers dancing on the keys quickly and accurately, playing and singing Perfect by British singer ed sheeran, Special Olympics’ hard-core head and unique singing voice, leaving a different memory for the audience.

　　At the first audio-visual feast of AI and art in China, AI brought us into a brand-new art world. Man-machine interaction, motion capture, virtual reality, holographic images, three-dimensional images and other technical means are combined with music, dance, opera and other artistic forms to jointly create a mirror world of light and shadow, and a visual spectacle of illusion.

　　However, when you listen carefully, the songs of Tianyi Luo and Special Olympics are still a little less natural and agile. Although the ups and downs of the vocal range can be realized by AI, the free flow and emotional expression of human voices can never appear on AI robots.

　　Artificial intelligence has greatly broadened the boundaries of art and made machines more like people. But "0" and "1" can’t teach machines to have unique human emotions. Without the artistic expression of emotion, it is difficult to really hit the hearts of the audience, and of course, it also makes people realize the "irreplaceable" of human voice.

　　On the Zhihu, someone asked: "What is the significance of developing AI production art?" Xiao Yao, the author of the science fiction "AI Trek", replied: "Artists will not disappear. AI will only eliminate some guys who are not innovative, and those who are truly capable and talented will only get better and better. If the artist’s creative enthusiasm will be hit by AI, it only means that it is normal for these guys to be eliminated. It’s like the appearance of a car is bound to hit ‘ Camel Xiangzi ’ Children, and part of ‘ Camel Xiangzi ’ I learned a driver’s license and became a taxi driver. "

　　interlinkage

　　Dialogue with Li Yuansu — —

　　Art still needs to return to the level of humanity and flesh.

　　Yangcheng Evening News: When did you start using AI for artistic creation? Are you satisfied with the results of this creation?

　　Li Yuansu: This is the first time I have combined with AI to create. With the theme of artificial intelligence, each of the three works has a clear experimental purpose: the mural of "AI Hegemony" is a struggle between hand painting and digital printing on the old media of "mural"; The game "AI Hegemony" uses the same material as murals, and the form is the game interaction mode in the "pre-AI era"; "Nanjing West Road Style Migration" uses contemporary cutting-edge AI technology. In this work, AI learns the artistic style independently and makes his own real-time creation. The three works show the aesthetic characteristics of different media from manual to digital, from static to interactive. The final result is to meet the expectations.

　　Yangcheng Evening News: What new possibilities does AI offer for artistic creation?

　　Li Yuansu: If we sum up the traditional appreciation of art as a group of relationships between artists and audiences, then this group of relationships in the AI era will be expanded, and we will have various combinations such as "machine creation-audience watching", "artist creation-machine watching" and "machine creation-machine watching". Of course, it is not easy to discuss whether machines can produce emotions and how to define emotions, but it is my purpose to do these works to explore along these lines.

　　Yangcheng Evening News: What do you think of the future artistic creation trend?

　　Li Yuansu: Now it seems that the role of artificial intelligence technology in human art will not be subversive. The role of AI in human art is expansion. It brings unprecedented media relations, creative materials, inspiration and great help. It allows human beings to better understand themselves in the mirror of science and technology. However, for the "machine art", recent years may only be the time when it originated.

　　Yangcheng Evening News: When artistic installations can continuously create works without the participation of artists, how should we treat these works of art? Is the painting made by artificial intelligence a real work of art?

　　Li Yuansu: The relationship between art and audience is consensual, and art is a condensed form of emotional experience. So, as long as someone is willing to admit that it is a work of art, it is. This is in essence. However, whether it is recognized academically or accepted by the art market will definitely lead to different situations and twists and turns.

　　Yangcheng Evening News: Is the essence of science and technology art art or technology? Will future artists be replaced by creative artificial intelligence machines?

　　Li Yuansu: Science and technology art is still art. In fact, today’s art is also inseparable from "technology". For example, canvas is a textile technology, and pigments need mineral and chemical technology, including photography and video, which were once high-tech — — Humans will always take everything at hand to create art and "play" art.

　　Artistic creation will not be replaced by machines. For creators, the first thing in art is to serve themselves, and it is an act of expressing emotions and recording experiences. In the contemporary era when information technology subverts the way of life, we are still trapped in the warmth of manual work. At present, only by returning to the level of humanity and flesh can the new media art gain the recognition of more audiences, and the pure aesthetics of science and technology is cold to most people.