夜无忧论坛官网

Li Yanming, a businessman from Yan ‘an, Shaanxi Province, was administratively detained by Baota Branch of Yan ‘an Public Security Bureau for 15 days in July this year and fined 3,000 yuan. Caixin. com previously reported that Li Yanming was not released after the detention. The family said that he was later taken away by the disciplinary Committee for investigation. During this period, Li Yanming suffered from closed head injury (severe) and bilateral occipital fractures due to his careless fall. On September 2nd, Li Yanming was arrested on suspicion of opening a casino. Since then, the family’s application for bail has been rejected.

On September 17th, Li Yanming’s attorney Qu Zhenhong provided The Paper with Li Yanming’s admission record. According to the record, Li Yanming was admitted to Xi ‘an Central Hospital at 16: 08 on August 3rd. "The patient said that he accidentally fell from the bed and landed on his pillow in the hotel. After the injury, he did not feel coma, vomiting, limb convulsions and dizziness. He was sent to our hospital after others found out. Head CT showed left occipital epidural hematoma, left cerebellar tentorium suspected subdural hematoma, right frontal lobe contusion, subarachnoid hemorrhage and bilateral occipital fracture. "

Admission records also show that Li Yanming has hypertension grade 2 (very high risk), left renal atrophy, aspiration pneumonia and so on. On August 3rd, Xi ‘an Central Hospital admitted Li Yanming with "closed head injury (severe)" and performed craniotomy on the same day.

Li Yanming’s hospitalization certificate

One month after the operation, Li Yanming was arrested. The notice of arrest served by the Baota Branch of Yan ‘an Public Security Bureau to Li Yanming’s family showed that "with the approval of the Baota District Procuratorate of Yan ‘an City, our bureau arrested Li Yanming on suspicion of opening a casino at 17: 00 on September 2, 2020, and is now detained in Xi ‘an Ankang Hospital." According to public information, Xi ‘an Ankang Hospital is a national secondary psychiatric hospital under the Xi ‘an Public Security Bureau and a designated medical hospital in the supervision place.

Li Yanming’s arrest notice

Qu Zhenhong told The Paper that she had applied to Ankang Hospital on September 7th to meet her client Li Yanming, but was told that Li Yanming was not allowed to meet a lawyer by the case-handling organ. I don’t know why. On September 18th, The Paper telephoned the police officer handling the Li Yanming case, trying to find out why the police refused to allow lawyers to meet Li Yanming, but the police officer said that he would not accept the interview and immediately hung up.

Qu Zhenhong told The Paper that on September 7, she also mailed an application for bail pending trial to the police officer of Baota Branch of Yan ‘an Public Security Bureau through EMS, but it was rejected on September 10.

After that, on September 14th, Li Yanming’s family went to Baota Branch to submit the application for bail pending trial. According to the application, after compulsory measures were taken, Li Yanming fell down on August 3, was diagnosed with closed head injury (severe), and underwent craniotomy on the same day. At present, Li Yanming’s physical condition is poor and he is not suitable for detention. In addition, Xi ‘an Ankang Hospital is a specialized psychiatric hospital, which mainly treats all kinds of mental patients and drug addicts, but it is incapable of treating Li Yanming’s illness.

In addition, the application also stated that Li Yanming’s alleged crime of opening a casino did not involve violent crimes, and taking measures to obtain bail pending trial would not cause social danger. He has opened a number of companies in Yan ‘an and has a fixed residence. He can be on call after being released on bail pending trial, which does not affect the police’s continued investigation of the case.

However, the above application for bail pending trial was rejected on the same day. The notice of compulsory measures not to be changed issued by Baota Branch of Yan ‘an Public Security Bureau said: "After review, our bureau believes that taking bail pending trial may destroy and falsify evidence and interfere with witnesses’ testimony or collusion; It may involve other new crimes, and the adoption of bail pending trial hinders investigation. According to the provisions of Article 97 of the Criminal Procedure Law, it is decided not to change the compulsory measures. "

Notice of police not to change compulsory measures

According to Caixin. com, Li Yanming, together with other representatives of small and medium-sized private enterprises in Yan ‘an, reported that several microfinance companies in Yan ‘an were involved in usury, black and evil and the umbrella behind them. The Yan ‘an Public Security Bureau set up a task force in 2019, and the case is still under investigation.

Beijing Zhengban Fa [2018] No.37

District People’s governments, municipal government commissions, offices and bureaus, and municipal institutions:

　　With the consent of the municipal government, the Beijing Action Plan for Accelerating Collaborative Innovation of Medical Health (2018-2020) is hereby printed and distributed to you, please conscientiously implement it according to the actual situation.

General Office of Beijing Municipal People’s Government

September 27, 2018

Beijing Action Plan for Accelerating Collaborative Innovation of Medical Health (2018-2020)

　　This action plan is formulated in order to thoroughly implement the State Council’s decision-making and deployment on promoting the healthy development of the pharmaceutical industry, conscientiously implement the Guiding Opinions of Beijing Municipality on Accelerating the Development of the Pharmaceutical and Health Industry through Scientific and Technological Innovation, further promote the high-quality development of the pharmaceutical and health industry in this city, and accelerate the construction of the collaborative innovation system of Industry-University-Research.

　　I. General requirements

　　(A) the guiding ideology

　　Comprehensively and thoroughly study and implement the spirit of the 19th National Congress of the Communist Party of China, take Socialism with Chinese characteristics Thought of the Supreme Leader in the New Era as the guide, conscientiously implement the spirit of the important speech delivered by the General Secretary of the Supreme Leader to Beijing, adhere to the new development concept, give full play to the advantages of science and technology and talents in the capital, follow the law of scientific and technological innovation and industrial development in medicine and health, aim at bottlenecks and common needs, and focus on key areas such as frontier technologies in life sciences, emerging industries where doctors and workers cross, and sophisticated pharmaceutical industries. Efforts will be made to deepen the reform of institutional mechanisms, gather innovative elements, strengthen collaborative innovation, optimize the business environment, and continuously improve the level of medical health innovation and development, providing strong support for building a national science and technology innovation center, building a sophisticated economic structure, and promoting high-quality development.

　　(2) Basic principles

　　Adhere to the problem orientation. Grasp the key links such as basic research, transformation of achievements and industrialization, deeply analyze the key and difficult problems faced by medical health innovation and development, make precise efforts, make comprehensive policies, fill shortcomings, strive to break down institutional and institutional obstacles, and effectively solve the "stuck neck" problem that restricts development.

　　Pay attention to original innovation. Grasp the frontier development trend of life science and biotechnology, focus on the research and development of innovative drugs and high-end medical devices, take universities and research institutes as the source of innovation, increase the intensity of basic research, strengthen the output of original achievements, and enhance the ability of independent innovation.

　　Strengthen collaborative transformation. Give full play to the advantages of innovative resources, especially medical innovative resources, and carry out collaborative research with major clinical application needs as the traction; Actively guide medical institutions to strengthen cooperation with enterprises, smooth the channels for the transformation of scientific research achievements of medical institutions, realize the collaborative innovation of Industry-University-Research medical institutions, and effectively promote the transformation of achievements.

　　Promote high-end development. Accelerate industrial transformation and upgrading, vigorously promote the integration of medical health with artificial intelligence and big data technology, actively cultivate emerging formats, and provide new kinetic energy for industrial development; Intensify efforts to guide the gathering of various international innovation factors, actively promote the extension of industrial value chain to the high end, and optimize the construction of high-end industrial system.

　　(3) Development goals

　　By 2020, we will introduce and cultivate a number of world-class innovation teams and a number of key enterprises with strong independent innovation capabilities, and the original innovation capabilities will continue to lead the country; The professional incubation ability has been significantly improved, and the transformation system of scientific and technological achievements has become more sound; The innovation system and mechanism of medical institutions have been further improved, the level of clinical research has been greatly improved, and the spillover effect of medical resources has been significantly enhanced; The industrial policy has been further refined, the industrial elements have been further concentrated, the industrial environment has been further optimized, and the Industry-University-Research medical collaborative innovation system has taken shape; The scale of the industry has further expanded, with an additional development space of about 10 square kilometers, and the main business income has reached 250 billion yuan.

　　Second, the key tasks

　　(A) to strengthen basic research and achievements transformation, enhance innovation ability.

　　1. Increase support in key areas. In some frontier areas, new R&D institutions will be built, and at the same time, a number of scientific apparatus will be laid out to support the cultivation of original innovation achievements and accelerate the breakthrough of frontier technologies. Formulate a catalogue of key directions for collaborative innovation and development of medical health in Beijing, focus on supporting basic research such as stem cells and regenerative medicine, brain science and brain-like medicine, structural biology, synthetic biology and protein omics, promote the development of technologies such as immunotherapy, gene detection and new sequencing, multimodal and cross-scale biomedical imaging, and promote the development of innovative drugs, high-end medical devices, and the integration of medical health with artificial intelligence and big data technology. (Responsible unit: Municipal Science and Technology Commission, Municipal Health and Family Planning Commission)

　　2. Strengthen the professional incubation capacity building. Improve the incubation capacity of professional incubators in Beijing Economic and Technological Development Zone, Haidian District and Daxing District, and strengthen comprehensive services such as evaluation and consultation, intellectual property rights, law and finance. Pilot the construction of professional incubators in Zhongguancun Life Science Park and other parks, and select international operation management institutions; Actively promote the pilot experience and build a number of professional incubators in the concentrated areas of colleges and universities, research institutes and medical institutions. (Responsible units: Municipal Science and Technology Commission, Zhongguancun Management Committee, Municipal Education Commission, Beijing Economic and Technological Development Zone Management Committee and relevant district governments)

　　3. Accelerate the upgrading and construction of Zhongguancun Life Science Park. Establish the strategic steering committee of Zhongguancun Life Science Park, and improve the management structure and working mechanism of the park. Optimize and upgrade the service functions of Zhongguancun Life Science Park in the first and second phases, and start the planning and construction of the third phase. Introduce international park management service team, third-party R&D and production service enterprises, professional intermediaries, social capital and other supporting elements, actively create a world-class innovation and development environment in line with international standards, and strive to make Zhongguancun Life Science Park a professional park with global influence, providing strong support for strengthening original innovation in the field of medicine and health. (Responsible units: Zhongguancun Management Committee, Municipal Science and Technology Commission, Haidian District Government, Changping District Government, Zhongguancun Development Group)

　　(B) improve the level of clinical research, play a spillover effect.

　　4. Improve the level of clinical research and experiment. Further speed up the layout of the national and Beijing clinical medical research centers and give full play to their leading role in clinical research. Adopt the co-construction mode of medical institutions, universities, scientific research institutes and enterprises, introduce an international operation management team, pilot the construction of independent clinical trial hospitals, and actively explore the sustainable operation mechanism. Support tertiary medical institutions to set up research wards to carry out high-level clinical medical research; On the basis of the existing drug clinical trial institutions, explore the establishment of clinical trial collaborative network in various ways to solve the problem of insufficient resources such as clinical trial beds in tertiary medical institutions and effectively support the needs of clinical trials. (Responsible units: Municipal Health and Family Planning Commission, Municipal Science and Technology Commission, Municipal Finance Bureau, Municipal Food and Drug Administration, Municipal Hospital Administration, Zhongguancun Administrative Committee, Beijing Economic and Technological Development Zone Administrative Committee, Changping District Government, Haidian District Government)

　　5. Optimize the system and mechanism of scientific and technological innovation in medical institutions. Promote the transformation of clinical trials and results as an important basis for the performance evaluation of medical institutions and the evaluation of personnel titles. We will adjust and improve the post setting of medical institutions, the pricing of scientific and technological achievements, the distribution of income disposal, and the exemption of key management personnel from due diligence, and issue detailed rules for the implementation of medical institutions to encourage scientific and technological innovation and the transfer and transformation of achievements. Improve the construction standards of scientific research houses in medical institutions, and ensure the scientific research land of medical institutions undertaking clinical trials. (Responsible units: Municipal Health and Family Planning Commission, Municipal Development and Reform Commission, Municipal Planning and Land Commission, Municipal Finance Bureau, Municipal Hospital Administration, Municipal Human Resources and Social Security Bureau, Beijing Economic and Technological Development Zone Administrative Committee and relevant district governments)

　　6. Guide medical institutions to accelerate the transformation of results. Strengthen the collaboration between medical institutions and enterprises, and explore the establishment of a collaborative innovation research institute for medical health to promote the transformation of scientific and technological achievements. Explore the establishment of medical health innovation and transformation funds by medical institutions, joint ventures, social capital, industrial technology alliances, etc., to support medical science and technology innovation and transformation of achievements. (Responsible units: Municipal Health and Family Planning Commission, Municipal Hospital Administration, Municipal Science and Technology Commission, Municipal Finance Bureau)

　　7. Promote the co-construction and sharing of medical and health data. On the basis of the clinical data and sample database of major diseases in Beijing, we will build a unified, open and shared biological sample database, a health big data center and a digital clinical research network in the city to promote the standardization of clinical medical data and the open interoperability of inter-hospital data. (Responsible units: Municipal Health and Family Planning Commission, Municipal Hospital Administration, Municipal Science and Technology Commission, Municipal Economic Information Commission)

　　(C) focus on cultivating key enterprises to enhance core competitiveness

　　8. Strengthen the overall service of key enterprises. Strengthen the follow-up service for key enterprises, keep abreast of the development trends and needs of enterprises, strengthen departmental linkage and policy integration, and solve the problems encountered by enterprises in the process of R&D, production and operation in a timely manner by means of "one enterprise, one policy, one thing and one discussion". (Responsible units: Municipal Science and Technology Commission, Municipal Economic Information Commission, Municipal Health and Family Planning Commission, Zhongguancun Management Committee, Beijing Economic and Technological Development Zone Management Committee, Municipal Food and Drug Administration, Municipal Human Resources and Social Security Bureau, Municipal Finance Bureau)

　　9. Promote the innovation and development of R&D enterprises. Study and establish a green channel for the approval of innovative varieties, and coordinate and accelerate clinical trials; After the varieties are mature, we will support R&D enterprises to develop into production-research integration enterprises, build high-end product production lines, and promote the transformation and large-scale production in Beijing. (Responsible units: Municipal Science and Technology Commission, Municipal Economic Information Commission, Municipal Food and Drug Administration, Beijing Economic and Technological Development Zone Administrative Committee, and relevant district governments)

　　10. Support production enterprises to become stronger and bigger. In terms of production line upgrading, scale expansion of listed varieties, secondary development of key varieties, international market expansion, listing financing and mergers and acquisitions, we will increase support to promote enterprises to continuously enhance their core competitiveness. (Responsible units: Municipal Economic Information Commission, Municipal Science and Technology Commission, Municipal Finance Bureau, Zhongguancun Management Committee)

　　11. Strengthen third-party R&D and production services. Introduce high-end service-oriented institutions or teams at home and abroad, and encourage the construction of third-party R&D service platforms and OEM service platforms that meet international standards; Strengthen policy guidance, provide support for international certification of platform technical standards and quality specifications, and ensure supporting conditions such as capital, land and factory buildings. (Responsible units: Municipal Economic Information Commission, Municipal Science and Technology Commission, Zhongguancun Management Committee, Municipal Finance Bureau and Municipal Environmental Protection Bureau)

　　12. Accelerate the establishment of production and professional service platforms. In Haidian District and Changping District, a thousand-liter pilot service platform for biopharmaceuticals will be built to meet the demand for commissioned production of scientific research samples and clinical trials of innovative subjects. In Beijing Economic and Technological Development Zone, relying on professional service enterprises with strong existing technical strength and complete software and hardware conditions, we will build a 100,000-liter biopharmaceutical OEM production service platform to realize the large-scale production of antibody drugs and cell therapy drugs. (Responsible units: Municipal Science and Technology Commission, Municipal Economic Information Commission, Zhongguancun Management Committee, Municipal Environmental Protection Bureau, Beijing Economic and Technological Development Zone Management Committee and relevant district governments)

　　13. Support the development of multinational companies in Beijing. Make full use of the international cooperation channels of universities and research institutes, actively connect with the world’s top medical and health multinational companies, and support them to build their headquarters and R&D centers in Beijing. Focusing on the strategic adjustment of R&D centers of multinational companies, we will do a good job in docking services and adopt various cooperation modes to promote talent teams and key projects to land in Beijing. (Responsible units: Municipal Science and Technology Commission, Zhongguancun Management Committee, Municipal Economic Information Commission)

　　14 to promote the innovation and development of Chinese medicine industry. Relying on the institutions of higher learning and scientific research institutes in the field of traditional Chinese medicine in this city, we will promote the integration of traditional Chinese medicine theory and modern science, strengthen the construction of modern technology platforms such as the design and optimization of traditional Chinese medicine and the system control of pharmaceutical process, and further increase the research and development and transformation of classic prescriptions of traditional Chinese medicine and in-hospital preparations. Give play to the leading role of leading enterprises in innovation, strengthen the research and development of new Chinese medicine and the secondary development of large varieties of Chinese medicine. Support Chinese medicine enterprises to use standardized, automated and intelligent technologies to transform and upgrade traditional processes, and give full play to the preventive and therapeutic effects of Chinese medicine on major chronic diseases, difficult diseases and senile diseases. (Responsible units: Municipal Administration of Traditional Chinese Medicine, Municipal Science and Technology Commission, Municipal Economic Information Commission)

　　(D) Improve industrial development factors and optimize the business environment.

　　15. Promote the development of industrial agglomeration. The relevant areas that list the medical and health industry as the leading industry should make strategic plans for industrial development as soon as possible, make clear the new space and speed up the industrial layout. The northern part (Haidian District and Changping District) should give full play to the scientific research advantages of Zhongguancun Science City in basic research and cutting-edge technology of medicine and health, and form a strong support for industrial development; In the southern part (Beijing Economic and Technological Development Zone and Daxing District), in the planning and utilization of land space, we should strengthen the guarantee for the development of medical and health industry, guide the centralized layout of enterprises and projects, and further enhance the advantages of high-end manufacturing agglomeration. (Responsible units: Municipal Economic Information Commission, Municipal Development and Reform Commission, Municipal Planning and Land Commission, Zhongguancun Management Committee, Municipal Environmental Protection Bureau, Beijing Economic and Technological Development Zone Management Committee, relevant district governments and Zhongguancun Development Group)

　　16. Optimize the service system of the park. Strengthen the evaluation of medical and health professional parks, further clarify the functional orientation of parks, and strengthen the planning and service system construction of parks. R&D parks should strengthen the construction of soft environment, build investment and financing platforms, one-stop comprehensive service platforms and international exchange and cooperation platforms, and create an open and shared academic environment; Manufacturing parks should rationally arrange industrial space, speed up "changing cages for birds", build a service platform for OEM production, and strengthen the professional service capacity building of parks. Actively hold industrial forums and academic activities with international influence to build a platform for investors, scientists and entrepreneurs to communicate. Further improve the service level of the "one-stop" public service platform for entry and exit inspection and quarantine of special articles and biological materials of animal and plant origin in Zhongguancun Life Science Park and the "biochemical reagent Centralized Supervision Platform for Entry and Exit" of Zhongguancun International biochemical reagent Logistics Center in Beijing Economic and Technological Development Zone, and improve customs clearance efficiency. (Responsible units: Zhongguancun Management Committee, Municipal Economic Informatization Committee, Beijing Economic and Technological Development Zone Management Committee, relevant district governments and Zhongguancun Development Group)

　　17. Encourage the procurement and application of innovative products. Study and formulate evaluation and screening standards and identification procedures for innovative products of medical health, form a catalogue of new technologies and new products (services) in the field of medical health, and promote their inclusion in policy support systems such as government procurement and popularization and application. Municipal medical institutions set up a rapid evaluation and approval system for the procurement of innovative products on a pilot basis, and encourage the procurement of products in the catalogue of new technologies and new products (services) in the field of medicine and health. Conscientiously implement the Opinions of the General Office of the State Council on Improving the National Essential Drug System (Guo Ban Fa [2018] No.88), and actively promote the inclusion of innovative products and drugs that have passed the consistency evaluation in the national and municipal essential drug lists. (Responsible units: Municipal Science and Technology Commission, Municipal Health and Family Planning Commission, Municipal Food and Drug Administration, Zhongguancun Management Committee, Municipal Economic Information Commission, Municipal Finance Bureau, Municipal Hospital Administration, Municipal Human Resources and Social Security Bureau)

　　18. Optimize the price management methods of new medical services. Deepen the reform of medical service price, speed up the formulation of detailed rules for the implementation of price management of new medical service items in public medical institutions in this Municipality, explore the implementation of dynamic management, and speed up the evaluation of new diagnosis and treatment technologies and products with strong innovation and high clinical application value when approving new medical service charges. (Responsible unit: Municipal Health and Family Planning Commission, Municipal Development and Reform Commission)

　　19. Accelerate the implementation of the drug listing license holder system. According to the requirements of the State Council on the pilot system of drug marketing license holders, we will speed up the formulation of implementation plans from the aspects of review, approval, supervision and management, further encourage drug innovation and improve drug quality. (Responsible units: Municipal Food and Drug Administration, Zhongguancun Management Committee)

　　20. Increase innovation incentives. Relevant areas with the medical and health industry as the leading industry should study and introduce measures to give corresponding incentives to enterprises whose main business income reaches a certain scale for the first time, whose major innovative varieties are first approved for listing in China or approved for listing in European and American countries, and whose generic drugs pass the consistency evaluation. (Responsible units: Municipal Economic Information Commission, Zhongguancun Administrative Committee, Municipal Food and Drug Administration, Beijing Economic and Technological Development Zone Administrative Committee and relevant district governments)

　　Third, safeguard measures

　　(1) Strengthen overall coordination. Establish a joint meeting system, regularly consult and dispatch, coordinate and promote the collaborative innovation of medical health in this city, coordinate and solve key and difficult problems in industrial development in a timely manner, and ensure the effective implementation of the action plan. Set up an expert steering Committee to provide advice on the organization and implementation of the action plan.

　　(2) Pay close attention to the implementation of tasks. Relevant municipal departments and relevant district governments should conscientiously perform their duties, formulate supporting policies and measures and refine the implementation plan in light of the actual situation. The municipal government authorizes Beijing Economic and Technological Development Zone, Haidian District, Daxing District and Changping District to independently decide on individual projects with total government support of less than 1 billion yuan. Establish a dynamic assessment system, include the completion of the action plan in the assessment index system of relevant departments and districts, strengthen inspection and evaluation, and promote the implementation of the action plan.

　　(3) Strengthen talent support. Select top talents and teams with international influence, and provide continuous and stable support through the establishment of Beijing Medical Health Frontier Innovation Project. Give full play to the role of various talent training platforms, and strive to train a group of high-quality and high-level management talents with international vision. Strengthen the service of top talents and teams in the field of medicine and health, and do a good job in supporting medical care, education and housing.

　　(4) Do a good job in ensuring funds. Focus on innovative drugs, high-end medical devices, and original innovations in the fields of medical health, artificial intelligence, and big data technology, and increase financial investment at the urban level. Relying on Beijing Science and Technology Innovation Fund to set up sub-funds in the field of medicine and health, attract social capital to participate, and actively support innovative projects at different stages. Strengthen investment and financing services such as listing, mergers and acquisitions, and broaden financing channels for enterprises.

Every editor, every reporter Zhao Yangge　　　　

Every reporter Zhao Yangge

Liaoning Zhenlong Specialty Co., Ltd. (hereinafter referred to as Liaoning Zhenlong), a company mainly engaged in the processing and sales of seed kernel series products and other dried fruits and nuts, published its prospectus in official website, China Securities Regulatory Commission on April 23, 2014. After waiting for nearly two years, it was not the listing road, but the filing inspection.

The company faces many risks.

A piece of news is going viral. According to many media reports, such as China, a brokerage firm, Liaoning Zhenlong IPO was investigated for alleged fraud, and Cinda Securities, as its sponsor and lead underwriter, was also implicated, and was also investigated by the CSRC before January 26, 2016. Cinda Securities has also confirmed the relevant information to the media.　

According to public information, the prospectus of Liaoning Zhenlong was signed on April 22, 2014, and the website of the CSRC was disclosed on April 23, 2014.

On March 13th, 2015, China Securities Regulatory Commission issued the "Information Disclosure Quality Spot Check and Lottery of Initial Public Offerings", including Liaoning Zhenlong and Sichuan imperial ware Co., Ltd..

It is reported that Liaoning Zhenlong was established on October 17, 2000, with legal representative Huang Yue and registered capital of 80 million yuan. Its main business is the processing and sales of seed products and other dried fruits and nuts, including pumpkin seeds, pine seeds and sunflower seeds. Nut products such as pistachios; Pumpkin seeds, pumpkin noodles and other pumpkin seed series comprehensive utilization products and other products such as beans and miscellaneous grains. The company mainly exports, and the data show that its export income once accounted for 80% of its main income, and its products were sold to Germany, the Netherlands, the United States, Canada, Australia and South Korea. According to Liaoning Zhenlong, the top five customers of the company in 2013 were all abroad.

National business daily reporter noted that based on Liaoning Zhenlong’s own business situation, the company faces many risks:

First of all, because the company’s main raw materials are agricultural products such as pumpkin seeds and nuts such as pine seeds, the cost of raw materials accounts for 90% of the main business cost, so when the output of raw materials needed for production is affected by climate, planting area and other factors, it is inevitable that the company’s purchase price will fluctuate greatly. This year-by-year cost change from 2011 to 2013 disclosed by Liaoning Zhenlong can be seen.

Secondly, because of the consideration of raw material planting and other factors, Liaoning Zhenlong needs to store raw materials, and the fourth quarter of each year to February of the following year is the centralized procurement period of raw materials. Seasonal centralized procurement is a remarkable feature of the company’s raw material procurement, and the proportion of raw material inventory amount to raw material procurement amount is about 30%. This kind of seasonal purchase is large, and the raw materials are stored for a long time. The company has the risk of deterioration and damage of raw materials due to insufficient storage space, abnormal climate or lax storage management.

In addition, because Liaoning Zhenlong mainly exports, the change of exchange rate will undoubtedly have an impact on the company. According to the data disclosed by the company, the exchange losses from 2011 to 2013 were 2,710,800 yuan, 1,694,900 yuan and 9,563,500 yuan respectively, which will undoubtedly affect the company’s profitability. At the same time, because the products are mainly exported, the company also faces the risk of changes in the export tax rebate policy.

Agricultural stock fraud is "more impulsive"?

Interestingly, as an agricultural enterprise, Liaoning Zhenlong is not an isolated case, and many agricultural enterprises have made frauds before.

After consulting the public information, the reporter of national business daily found that as early as 1994, Yinguangxia, known as the "first blue chip in China", had inflated profits by 772 million yuan from 1998 to 2001, and its share price (after being reinstated) rose from around 2.5 yuan in 1998 to nearly 25 yuan at the end of 2001. After the fraud incident, its share price plummeted again, falling short of 0.5 yuan.

Lantian shares, the "first agricultural stock in China" listed in June 1996, once created the "myth" of the capital market with its "excellent performance". The fact is that in 1999 and 2000, the company’s fictitious operating income was 3.69 billion yuan (actually only 64 million yuan) and its fictitious net profit was 940 million yuan (actual loss).

In 2005, Fengle Seed Industry, which had been listed for 8 years, was found to have been faked for 6 years, with fictitious main income of 180 million yuan and inflated net profit of 40.06 million yuan.

In 2006, Grassland Xingfa was listed for 9 years, and accumulated inflated net assets of 1.415 billion yuan, and at the same time fabricated operating income and costs.

In 2011, Green Land became the first case of small and medium-sized board fraud, which also alarmed the market with inflated assets and revenue.

From 2008 to 2011, Wanfushengke accumulated inflated income of about 740 million yuan and inflated net profit of about 160 million yuan, which was called "the first stock of fraud on GEM".

According to Ruilin’s investment research, many agricultural stock frauds are worthy of market consideration: First, the infrastructure construction, raw material procurement and sales involved in the business activities of agricultural enterprises mainly involve individual farmers and small farmers’ cooperative organizations. This determines that the trading objects of such enterprises are extremely scattered, and the trading means need to use a lot of cash, and their business flow and cash flow are not as clear and strict as those of other industrial and commercial enterprises, which has caused fundamental difficulties in auditing; Second, in order to encourage the development of agricultural production and agricultural products processing industry, the state has implemented many preferential tax policies, and the tax rate of agriculture is very low, even some areas are completely tax-free, which will greatly reduce the tax cost of fraud. However, industries without tax incentives need to pay more than 10% of sales. In order to make fraud, companies in these industries must pay a lot of real money to pay taxes for several years, and the cost of fraud is high; Third, the operating profit rate of agricultural enterprises is generally low, and if the market is slightly disturbed, enterprises may lose money, and the profit pressure of enterprises is greater than other enterprises. Moreover, the cyclical characteristics of agricultural enterprises, especially aquaculture, are very obvious, and it is difficult for enterprises to maintain stable profit growth. In order to maintain a good image of sustained profit, companies have a stronger impulse to falsify.

Beijing Municipal Bureau of Civil Affairs Beijing Municipal Bureau of Human Resources and Social Security

Beijing Municipal Bureau of Finance on Perfecting Land Expropriation and Over-transfer Personnel

Opinions on medical treatment and management related issues

Jing Min Zheng Fa [2012] No.503

County Civil Affairs Bureau, Human Resources and Social Security Bureau, Finance Bureau:

In order to further improve the medical treatment and management of land acquisition, rural resettlement and over-transfer personnel (hereinafter referred to as over-transfer personnel) in this Municipality, with the consent of the municipal government, we hereby put forward the following opinions.

　　1. All the former rural laborers who have been converted into resident households due to land acquisition for national construction, including the elderly who have no dependents and the sick and disabled who have lost their working ability within the legal working age, who are over the resettlement period (men over 60 years old, women over 50 years old and above), shall be treated with a card with reference to the Provisions of Beijing Municipality on Basic Medical Insurance (Order No.158 of Beijing Municipal People’s Government) and relevant policies and regulations. The medical treatment of the sick and disabled who have not reached the retirement age in the over-transfer personnel shall refer to the standards for retirees of urban workers’ basic medical insurance enterprises.

　　Two, to issue social security cards for over-transfer personnel, and to issue cards for the first time without personal expenses. In the future, the expenses related to the replacement of cards due to damage or loss shall be borne by the overstaffed personnel. The specific use management shall be implemented in accordance with the relevant policies and regulations of the human resources and social security department of this Municipality.

　　Three, by the social insurance agencies with reference to the basic medical insurance standards, establish a personal account for the ultra-transfer personnel, over 70 years old (inclusive) ultra-transfer personnel will be paid 107 yuan per person per month, and under 70 years old ultra-transfer personnel will be paid 97 yuan per person per month, which will be included in the personal account passbook of the ultra-transfer personnel on a monthly basis, and the original medical subsidy for the general ultra-transfer personnel will be cancelled.

　　Four, super transfer personnel to enjoy medical treatment with reference to the basic medical insurance for urban workers and other matters, in accordance with the "Beijing basic medical insurance regulations" (Beijing Municipal People’s Government DecreeNo. 158th) and related policies and regulations. Refer to the implementation period, regardless of the payment period.

　　Five, lonely old hospitalization, emergency observation, outpatient special disease Qifubiaozhun the following expenses, personal payment of medical expenses (excluding personal payment of the door, emergency Qifubiaozhun the following expenses and personal payment at their own expense), by the civil affairs department to give supplementary reimbursement, supplementary reimbursement of funds required by the original channel expenses.

　　Six, super transfer personnel in accordance with the principle of "nearest medical treatment", within the scope of designated medical institutions of basic medical insurance, choose four designated medical institutions for individual medical treatment, among which there must be a community health service center (station) or grass-roots designated medical institutions such as factories, mines, universities and other internal services. Class A hospitals, traditional Chinese medicine hospitals and specialized hospitals in the designated medical institutions in the city are common designated medical institutions, and they can seek medical treatment without selection. The first consultation system of designated community health service institutions in general outpatient clinics shall be implemented for over-transfer personnel to seek medical treatment.

　　Seven, the medical management of the ultra-transfer personnel shall refer to the relevant provisions of the basic medical insurance for urban workers.

　　Over-transfer personnel must hold a social security card issued by the social insurance agency for medical treatment. The audit and settlement of medical expenses of over-transferred personnel shall be implemented with reference to the settlement method of basic medical insurance.

　　Eight, social insurance agencies to establish a special account for medical expenses of the overstaffed personnel, used to account for the basic medical personal account expenses and medical expenses of the overstaffed personnel, and the municipal, district and county civil affairs bureaus to which the overstaffed personnel belong as independent units, and make detailed accounting according to the municipal, district and county respectively.

　　Nine, the Civil Affairs Bureau in conjunction with the Municipal Human Resources and Social Security Bureau shall, before the end of November each year, determine the per capita expenditure budget standard for the medical treatment of the over-transferred personnel in the next year, calculate the number of over-transferred personnel based on the management of the municipal, district and county, and approve and determine the amount of funds payable by the municipal, district and county in the next year according to the principle of "more than enough to make up for less". Before December 15th of each year, the municipal, district and county shall pay the funds needed for the medical treatment of the overqualified personnel to the Municipal Finance Bureau according to the determined amount.

　　Ten, the Municipal Finance Bureau does not set up a separate special account for the management of medical treatment of the ultra-transfer personnel. In the existing social security account, the medical funds of the ultra-transfer personnel are accounted for separately, which is used to account for the medical treatment funds paid in by the municipal, district and county respectively and the medical treatment expenditure funds allocated to the municipal social insurance agency.

　　The social security account information of the Municipal Finance Bureau is as follows:

　　Account name: Beijing Municipal Bureau of Finance

　　Account number: 01090520500120111018246

　　Bank of deposit: Bank of Beijing Business Department.

　　Eleven, the Municipal Civil Affairs Bureau, the Municipal Human Resources and Social Security Bureau, and the Municipal Finance Bureau jointly pay attention to the operation of funds for medical treatment of over-transfer personnel during the year, predict in advance the temporary turnover difficulties of funds caused by special factors, and study and solve them in time through one-on-one discussion. The required funds will be borne by the municipal, district and county managers respectively.

　　Twelve, the newly received super-transfer personnel shall go through the registration and warehousing procedures at the social insurance agency in the district and county from the 5th to 25th of the month of receiving. From the second month after completing the registration, the overstaffed personnel shall refer to the Provisions of Beijing Municipality on Basic Medical Insurance (Order No.158 of Beijing Municipal People’s Government) and relevant policies and regulations, and enjoy medical treatment with the certificate of obtaining a new [replacement] social security card. Medical expenses incurred before holding a social security card for medical treatment can be settled by manual reimbursement at the street social security office of the contestant.

　　Thirteen, before going through the insurance formalities, other medical insurance personnel have been enjoyed. After going through the insurance formalities, the original medical insurance benefits will be stopped. With reference to the Beijing Basic Medical Insurance Regulations (Order No.158 of the Beijing Municipal People’s Government) and related policies, they will enjoy new medical benefits, and the threshold, reimbursement ratio and maximum payment limit need to be recalculated.

　　Fourteen, districts and counties to receive the funds needed for the medical treatment of over-transferred personnel should be paid to the Municipal Finance Bureau in accordance with the budget standard for the per capita expenditure of medical treatment of over-transferred personnel this year before the 10th day of the next month, according to the calculation of the number of new recipients, in accordance with the aforementioned prescribed procedures. The district/county civil affairs department shall, after determining the situation of new recipients in the current month, promptly consult the district/county financial department to turn over the funds needed for medical treatment. The district and county civil affairs departments shall also report to the Municipal Civil Affairs Bureau for statistics and summary of the new personnel in the city in that month, and the Civil Affairs Bureau shall file with the Municipal Finance Bureau before the end of the month as the basis for checking the funds paid by the new personnel next month.

　　Fifteen, the financial department, the auditing department and the social insurance administrative department shall, in accordance with their respective duties, supervise the income and expenditure and management of the medical treatment funds for the over-transferred personnel.

　　Sixteen, the basic medical personal account standards, medical expenses Qifubiaozhun, reimbursement ratio and the maximum payment limit and other policy adjustments, the corresponding standards of overstaffed personnel shall be adjusted at the same time.

　　This opinion shall come into force as of January 1, 2013.

Beijing Municipal Bureau of Civil Affairs Beijing Municipal Bureau of Human Resources and Social Security

beijing finance bureau

December 10, 2012

China. com May 14th-Fantasy, Cultivation of Immortals, Crossing … In the modern society with the rapid development of the Internet, a new novel type, online novel, has become a "household name". Network literature is very different from traditional literature in style, and it can cover a wide range. With the development of the Internet age, people’s demand for reading and entertainment is changing, and online novels are quickly loved by readers, surpassing other novel categories and becoming the first novel group in China.

Online novels are popular in China.

The Japanese Modern Business Network published an article on May 13th, saying that the online literature market is very active in China. The online literature market in China is much larger than that in Japan, with more than 300 million users. At present, China’s largest original literature website "qidian" has reached about 1.5 billion hits per day. This is equivalent to one month’s hits of "Become a Novelist", the largest original novel website in Japan.

The article also points out that the update speed and market scale of China’s novel websites are unmatched by Japan. The number of online novel authors in China is very considerable, with an average of more than 200 million words per day, and new works are constantly being put on the shelves. Some of the writers’ works will also be adapted into games, film and television dramas, etc.

The American Wall Street Journal also published an article saying that in China, the Internet is not only used to play video games, watch videos, etc., but it is also being vigorously promoted as another pastime-reading novels.

According to the article, online novels are becoming one of the powerful forces in shaping popular culture in China. It is also an attractive asset for Internet companies with film production companies, video websites and video game development companies.

According to the analysis of The Wall Street Journal, there are similarities between China’s online literature and the development model of e-commerce. The popularity of online novels may be because it meets the needs of "local science fiction, fantasy and romance" that are ignored by traditional domestic publishing houses.

Foreign authors join the creative army.

In May 2017, the starting point was launched internationally. It is aimed at overseas users, mainly in English.

The Reading Group (the parent company of the starting point network) recently released the "2018 Network Literature Development Report". According to the report, up to now, more than 12,000 overseas authors have registered internationally at the starting point, and more than 19,000 original English works have been reviewed. The world outlook structure of most of these works is deeply influenced by China’s online writings, which contains China cultural elements such as striving for blood and respecting teachers.

China Daily reported that foreign writers joined China’s online writing army because of their love for China culture and demand. Although China’s "going out to sea" is only a few short years, its global fan base has been considerable. For example, the users of Qidian International have spread all over the world, and the cumulative number of visiting users has exceeded 20 million. As early as 2016, the cumulative number of hits in the world of martial arts, the pioneer of online translation in China, exceeded 500 million. Some people even listed China’s online articles as "the four cultural wonders of the world" along with American Hollywood blockbusters, Japanese anime and Korean idol dramas. (Li Jinqiu)

Heilongjiang province people’s social welfare department talks about the US Mission online.

　　Cctv news(Reporter Li Wenxue): Recently, the problem of arrears of wages reflected by American group riders in Heilongjiang Province has aroused widespread concern in society. In order to further understand whether there are problems such as wage arrears, and the protection of employment and rider rights and interests of the US delegation, the People’s Social Welfare Department of Heilongjiang Province held a video conference on March 28 to conduct an online interview with the US delegation. This is also the first interview with platform companies by the human and social departments to promote the healthy development of new employment forms since the implementation of the Guiding Opinions on Safeguarding the Labor Security Rights and Interests of Workers in New Employment Forms.

　　On December 17th, 2021, the Department of Human Resources and Social Security of Heilongjiang Province, together with seven provincial departments, issued the Implementation Opinions on Safeguarding the Labor Security Rights and Interests of Workers with New Employment Forms, and put forward 20 measures to safeguard the rights and interests of workers with new employment forms, such as network distributors, network car drivers, truck drivers and Internet marketers, in guiding enterprises to standardize employment, improving employment security system and optimizing public service measures.

　　On March 5 this year, some workers sent a video through a social platform, reflecting the problem of wage arrears of the US Mission. On March 8, a website reported that the US Mission was in arrears with wages and bonuses and could not get a rest. On March 25th, a social platform appeared again, which reflected that the Meituan takeaway site in Acheng District of Harbin owed more than 30 people wages.

　　After paying attention to the problems reflected on the Internet, the People’s Social Welfare Department of Heilongjiang Province read the labor service agreement signed by the rider of Acheng Meituan and Harbin Puhong Technology Co., Ltd., and found that there were some irregularities in the content, such as the simple expression of the agreement, the unequal rights and obligations of both parties, and some obviously unfair clauses for workers.

　　At the online interview on March 28th, Meituan explained the issues related to the rider’s labor security rights and interests, such as labor and employment, wage payment, social security payment, working hours, rest and vacation, and the unpaid wages reflected by Meituan riders in Acheng District.

　　According to reports, the focus of the above-mentioned related events is that there is a dispute between Harbin Puhong Technology Co., Ltd., a partner of Meituan Platform, and the takeaway rider in accounting for salary. In view of the fact that the wage payment date agreed by both parties is 25th of each month, and it has been paid normally on 25th of February, according to relevant laws and regulations, if the wage is paid normally on the wage payment date, it cannot be determined that there is wage arrears before the next wage payment date. In view of the disputes reflected by riders in the calculation of performance bonus, they can apply for labor arbitration according to law. Regarding the nonstandard labor service agreement, Meituan indicated that it would further urge the partners to standardize according to the interview requirements.

　　The Provincial People’s and Social Welfare Department pointed out that Meituan, as a new employment enterprise, should fully understand the importance and urgency of safeguarding the labor security rights and interests of workers in new employment forms, and should shoulder its due social responsibilities while pursuing its own interests and consciously safeguard the legitimate rights and interests of workers; While bringing employment opportunities to the vast number of workers in Heilongjiang, we should pay more attention to the labor security rights and interests of employees. It is necessary to further standardize the outsourcing enterprise contract and the labor service contract signed between the outsourcing enterprise and the rider, and check whether there are comprehensive, clear and specific provisions on the rider’s labor security rights and interests. If it is not done, it is necessary to carry out rectification and improvement, and actively seek the opinions of the people’s society, trade unions and other departments and workers to make the contract more reasonable, legal and compliant.

　　The Labor and Social Security Supervision Bureau of the Provincial People’s Social Welfare Department requires that the self-inspection and rectification should be reported before the end of April, and contracts with outsourcing enterprises and samples of labor contracts signed by outsourcing enterprises and riders should be provided.

　　The relevant person in charge of the US Mission said that it is necessary to actively shoulder social responsibilities, do a good job of implementation in light of the actual situation of the enterprise, take effective measures, safeguard the labor security rights and interests of new employees with practical actions, and truly implement the rights and interests of workers.

As a global strategic model, Cadillac CT5 is positioned in the luxury mid-size car market, competing with BMW 3 Series, mercedes benz c Class and Audi A4L. The Honda Accord is a mainstream medium-sized car, competing with Volkswagen Magotan, Toyota Camry and Nissan Teana. There are obvious differences in the positioning and brand image of the two models, so why do people compare them? What are the deep reasons behind this?

In terms of appearance, Cadillac CT5 adopts the forward-looking design language of ESCALA concept car. The family-style front face design is highly recognizable, and the huge black mesh is angular and full of three-dimensional sense. The split LED headlight group is highly recognizable, and the headlight structure is also very sharp and sporty. The body lines are smooth and full of tension, and the tail shape is simple and fashionable. On the whole, Cadillac CT5 shows a new American luxury sports style.

Honda Accord is a more traditional and conservative medium-sized car. It adopts Honda’s family-style front face design, the middle net adopts the combination of chrome-plated decorative strips and black grids, and the headlight group also adopts LED light source, which is connected with the middle net to form an integrated effect. The body lines are smooth and elegant, and the tail shape is also round and steady. On the whole, Honda Accord shows a classic and mature Japanese style.

As can be seen from the appearance, there are obvious differences in design concepts and styles between Cadillac CT5 and Honda Accord. Cadillac CT5 pays more attention to sportiness and individuality, while Honda Accord pays more attention to comfort and stability. This also reflects the different consumer groups that the two models face. Cadillac CT5 is more suitable for young consumers who pursue passion and innovation, like driving pleasure and brand image, while Honda Accord is more suitable for mature consumers who pursue safety and practicality and like comfort and reliability.

In terms of interior, Cadillac CT5 also continued its sports style. It adopts a similar embracing design, and the overall atmosphere also shows a certain sense of movement. As always, the interior materials of the new car are exquisite, and all the places that can be touched are covered with leather, such as the multifunctional leather steering wheel covered with luxury leather and the Moli leather seat, creating a comfortable and luxurious texture atmosphere. In terms of configuration, Cadillac CT5 supports dual Bluetooth device access, as well as CarPlay and CarLife functions. In addition, CT5 integrates a new generation of mobile internet experience CUE, which not only realizes OTA intelligent cloud update, but also matches the lifetime free traffic of 100G/ year, so that car owners can enjoy the latest information services anytime and anywhere.

The interior design of Honda Accord is simple and practical. It adopts a horizontal center console layout, which gives people a spacious and bright feeling as a whole. The interior materials of the new car are also exquisite and high-grade, and a large number of soft materials and wood grain decorative boards are used to enhance the interior texture. In terms of configuration, the Honda Accord is equipped with an 8-inch central control screen and supports CarPlay and CarLife functions. In addition, Honda Accord is also equipped with full LCD instrument panel, keyless entry, one-button start, power seat, rear air outlet, rear seat heating and other functions.

As can be seen from the interior, the design styles of Cadillac CT5 and Honda Accord also have different emphases. Cadillac CT5 pays more attention to technology and luxury, while Honda Accord pays more attention to simplicity and practicality. This also reflects the different values pursued by the two models. Cadillac CT5 is more suitable for young consumers who like to try new things and enjoy the convenience and fun brought by high technology, while Honda Accord is more suitable for mature consumers who like simple life and pay attention to functionality and practicality.

In terms of power, Cadillac CT5 adopts Smart Propulsion intelligent drive technology, equipped with a brand-new 2.0T four-cylinder turbocharged engine, with a maximum power of 174kW and a maximum torque of 350 N m. It is matched with a 10-speed automatic manual transmission, and its power output is smooth and strong. The new car is also equipped with an electro-hydraulic composite braking system, which can effectively improve braking performance and fuel consumption performance. In addition, Cadillac CT5 also has a variety of driving modes, including comfort, sports, snow, personalization, etc., which can be adjusted according to different road conditions and drivers’ preferences to provide a more personalized driving experience.

Honda Accord is equipped with a 1.5T four-cylinder turbocharged engine, with a maximum power of 142kW and a maximum torque of 260N·m, matching CVT continuously variable gearbox, and the power output is stable and economical. The new car is also equipped with Honda’s unique i-VTEC intelligent variable valve timing technology, which can effectively reduce fuel consumption and emissions. In addition, Honda Accord also has two driving modes, including economy and sport, which can be switched according to different driving needs, providing more flexible driving options.

As can be seen from the power, the performance parameters of Cadillac CT5 and Honda Accord also have obvious gaps. The engine displacement, power and torque of Cadillac CT5 are higher than those of Honda Accord, and the gearbox is more advanced and accurate. This also reflects the different driving feelings pursued by the two models. Cadillac CT5 is more suitable for young consumers who like passion and excitement and enjoy speed and control, while Honda Accord is more suitable for mature consumers who like stability and economy and pay attention to fuel consumption and environmental protection.

In terms of safety, Cadillac CT5 is not lost to any opponent. It adopts a new generation of ultra-high strength steel body structure, which can effectively improve the rigidity and safety of the body. The new car is also equipped with Super Cruise, a super intelligent driver assistance system, which is an advanced automatic driving system integrating adaptive cruise, automatic steering, automatic lane change and other functions, and can achieve unmanned driving effect on the highway. In addition, Cadillac CT5 also has a number of active and passive safety configurations, including front and rear reversing radar, reversing images, blind spot monitoring, lane keeping, collision warning, automatic emergency braking, etc., to provide all-round protection for drivers and passengers.

The safety performance of Honda Accord should not be underestimated. It adopts the advanced and compatible engineering body structure of ACE, which can effectively disperse the impact force and protect the space in the passenger cabin. The new car is also equipped with Honda SENSING intelligent safety assistance system, which is an active safety system integrating adaptive cruise, active braking, lane keeping, traffic sign recognition and other functions, and can achieve the effect of intelligent assisted driving under various road conditions. In addition, Honda Accord also has a number of active and passive safety configurations, including front and rear reversing radar, reversing images, blind spot monitoring, lane departure warning, collision mitigation braking, etc., to provide all-round protection for drivers and passengers.

As can be seen from the safety, the safety performance of Cadillac CT5 and Honda Accord is excellent. The safety technology of Cadillac CT5 is more advanced and leading, while that of Honda Accord is more mature and stable. This also reflects the different safety concepts pursued by the two models. Cadillac CT5 is more suitable for young consumers who like to try new technologies and enjoy intelligent driving, while Honda Accord is more suitable for mature consumers who like to trust old technologies and pay attention to practical driving.

To sum up, Cadillac CT5 and Honda Accord are two completely different models with different design styles, performance parameters, safety technologies and market positioning. They each have their own advantages and characteristics, and each has its own target consumer groups. Therefore, it is unfair and unreasonable to compare and evaluate them simply. Every consumer should choose the most suitable model according to his own needs and preferences. The price of Cadillac CT5 is amazing. You can buy a 5-meter luxury car for 220,000 yuan, which is not as good as Honda Accord. This sentence is just a marketing tool and should not be taken as truth. On the contrary, we should look at the real value of each model with a more objective and rational vision.

Zhu Yue Wei Mengge Zhongqing Bao Zhongqing Net reporter Sun Haihua

From the orangutans who like to live alone, to the gibbons with white palms, to the langurs with harem, and the cynomolgus monkeys who marry in groups, the primates’ views on marriage and love and the size of their social circle are very different. What kind of driving force has shaped this difference? This question was answered in the study of Asian langur by the team of Northwest University-

In the early morning of June 2nd, Science magazine published the latest research achievement Adaptations to a cold climate promoted social evolution in Asian colobine primates in the form of a long article, which systematically revealed the mystery of primate social evolution for the first time. The cover picture of this issue of Science shows the representative of Asian langur-Qinling golden monkey, and the picture is provided by the research team of Northwest University.

Restore the evolution history of Asian langur social system

"Primates have a complex and diverse social structure. Their social structure has a strong phylogenetic signal, and it has been deeply influenced by historical environmental upheaval and recorded in their genomes. " Qi Xiaoguang, a professor at the School of Life Sciences of Northwest University and co-first author of the paper, said at the press conference on related research results held by Northwest University on June 2.

"We have been focusing on the study of golden monkeys for more than 20 years, using the method of combining GPS collar, satellite remote sensing technology and social network analysis, and through long-term field tracking and observation, we have always wanted to uncover the mystery of primate society." Li Baoguo, a professor at Northwest University and co-correspondent, introduced.

After years of research, the team found that the golden monkey society has a unique four-layer social structure: family, detachment, group and community. In 2014, Qi Xiaoguang and Li Baoguo jointly developed a paper in the journal Nature-Communication, and put forward the hypothesis of "Asian origin-aggregation" for the first time, which broke the single understanding of the complex social origin of primates by western scholars and opened a new avenue for studying the evolution of animal social systems.

This time, the research team extended their eyes to 8 million years ago, and pieced together the diffusion path of Asian langur ancestors from the historical distribution suggested by biological fossils and the excavation of big data such as ancient sea level, ancient geography and ancient climate.

About 8 million years ago in Miocene, the ancestors of Asian langurs spread from Europe.

One of them spread from the Indian Peninsula to Southeast Asia, and this group divided into three genera, and retained the ancestral "single family group" social system of one male and many females.

The other branch spread to Yunnan, China in the late Miocene, and formed the base group of strange-nosed monkeys. With the cold events in the late Miocene in this area, their family groups were no longer mutually exclusive, and sometimes separated and sometimes aggregated, forming a heavy-class society.

Due to the lack of food, most of the strange-nosed monkeys later spread to the south and evolved into different species such as white-rumped langurs and proboscis monkeys. Today, although they live in warm areas of Viet Nam and kalimantan island, they still retain the structural feature of a class-heavy society.

At the same time, the golden monkey, a close relative who stayed in the north of China, drew closer social relations, cultivated long-term and stable ties between families, and evolved a real stratified society in the repeated glacial and interglacial cold events in the Pleistocene.

"We found that species living in cold environments tend to form larger communities, and two social aggregations occurred in the Late Miocene Cold Period and the Pleistocene Quaternary Ice Age, respectively, which indicates that cold events may have driven community aggregation." Qi Xiaoguang said that on this basis, the team put forward the social evolution history of the Asian langur "three acts". This discovery is also a systematic exposition of the hypothesis of "Asian origin-aggregation" put forward by the team.　

Why did you choose the Asian langur as the research object? Scientists have also given the best answer: Asian langur belongs to the Old World Macaca colobus subfamily, with a total of 55 species in seven genera, including four different social system types: monogamous society, polygamous society, stratified society and quasi-stratified society, which are distributed from tropical rain forest to temperate snow-capped mountains. The team believes that this group is a good model for studying the social evolution mechanism system of primates.

In order to do this research well, the team cooperated with universities, research institutes, zoos and other teams at home and abroad to analyze and investigate 2903 habitats of Asian langur, and analyzed the comprehensive ecological factors of 19 environmental variables extracted from each habitat, thus constructing the most comprehensive Asian ecological data set so far.

Establish a research framework of "behavior-ecology-genome"

In the long history of 8 million years, how did the repeated cold events drive the Asian langur to complete the community gathering? This needs to be confirmed by analyzing the genome data passed down from generation to generation.

In order to answer the questions, the team creatively established a brand-new research paradigm of "behavior-ecology-genome". They overcame many difficulties such as cross-discipline and cross-region, completed high-quality genome sequencing of seven representative species of Asian langur, and obtained the world’s first non-human primate genome at chromosome level, thus constructing accurate phylogenetic relationships.

"We combine the central principles of macroevolution’s biology and micro-molecular biology to explore the genetic mechanism behind the cold events driving community aggregation." Qi Xiaoguang said. Through comparative genomics and phylogenetic analysis, it is shown that the cold events in history have promoted the positive selection of energy metabolism and neurohormonal regulation-related genes in Asian langur, and evolved a more effective brain, neurohormonal regulation network. Among them, the gene changes related to oxytocin and dopamine transmitter system in the strange-nosed monkey group are particularly striking: the society of its group presents a two-step step polymerization model, from "polygamy" of its ancestors to the formation of separation.

The team found that in mammals, oxytocin and dopamine can strengthen the bond between mother and child. The cold effect triggered their adaptive changes, strengthened the bond between mother and baby, and prolonged the parental rearing of the strange-nosed monkeys in cold areas. At the same time, the friendly behavior between individuals has also been promoted, which has further promoted the gathering of single family groups to a heavy society. This result has also been verified by cell function experiments and behavioral experiments.

"For example, our Qinling golden monkeys, where the climate is cold and food is scarce, will have more behaviors of holding groups to keep warm and grooming each other. Such a neuromodulation mechanism also indirectly increases the individual’s friendly behavior and tolerance, thus promoting the gathering of family groups to a heavy society. " Qi Xiaoguang said.

This study integrates animal behavior, ecology, geology, comparative genomics and other multidisciplinary means, and completely reveals the evolution process, motivation and genetic basis of the complex social system of Asian langur. Its greater significance lies in the establishment of a new research paradigm of "behavior-ecology-genome", which provides a new way to understand the origin and evolution mechanism of primate social behavior, including human beings, and also opens up a new direction for the development of animal behavior.

As the reviewer of Science magazine commented: "The author has traced back the social evolution history of Asian langur completely through multidisciplinary methods, and comprehensively analyzed its ecological causes and genetic basis, which is unprecedented in the study of primates and vertebrates, and has opened up a new avenue for the field of social evolution."　

Stick to the original heart: "If you like it, you want to protect it."

It is Qi Xiaoguang’s greatest wish for many years to make such a beautiful Qinling golden monkey on the cover of Science for the whole world to see. In 1999, he joined the golden monkey research team of Northwest University, studied under Professor Li Baoguo, and became one of the pioneers in the field research of Qinling Golden Monkey.

"The first time I saw the golden monkey was during the winter vacation of my freshman year." After walking alone for 12 hours, Qi Xiaoguang finally saw them in the depths of the Qinling Mountains: "Wow, they jumped over my head-light yellow hair, light blue skin, pure eyes … so beautiful!" "If you like it, you want to protect it" has become his initial intention to study the golden monkey for more than 20 years.

In his early years, Qi Xiaoguang spent six or seven months every year in the Qinling Golden Monkey Base, crossing the mountains and sleeping around the clock, carefully observing every subtle movement of the Golden Monkey, and spared no effort to collect data and analyze the research results. It is also because they are stationed in the field base all the year round that they explore a set of methods suitable for the study of mountain primate behavior, which lays a key foundation for the follow-up research.

"In the past, the research on the evolution mechanism of primate social systems has always stayed at a purely macro level, lacking in-depth exploration of molecular mechanisms. It is precisely because of the lack of suitable research templates and genome-wide data that there has been no major breakthrough in its specific evolutionary mechanism, especially its genetic basis. " After consulting a number of experts in the animal field, Qi Xiaoguang and team experts began a lonely attempt. Trying to try and make mistakes again and again, overthrowing and reorganizing again and again … It was this time that led Wu Jinwei and Zhao Lan to explore together, which made Qi Xiaoguang unforgettable.

Finally, the team finally found a clue to break through the bottleneck in micro-molecular biology. In the face of an extremely huge, complicated and completely unfamiliar new field, the team is quietly making breakthroughs. "The artificial classification of disciplines makes us only see one side, but biological evolution itself will not be inevitable because of these artificial classifications, which also forces us to look at the process and practice of evolution with a comprehensive eye." Zhao Lan said.

On the campus of Northwest University, Qi Xiaoguang often communicates with the teachers and students of the team of Shu Degan academicians who studied CAMBRIAN fossils 500 million years ago. Although their research period spans hundreds of millions of years, it involves many dimensions, such as behavior, ecology, geology, fossils and heredity. As long as there is an intersection, he will be interested.

"In the future, we will continue to deepen the research on the evolution mechanism of primate social systems represented by Asian langurs, and then explore the origin and changes of early human society." Qi Xiaoguang is full of expectations.

　　Zhongxin. com, February 28th, "Look at this video, including Biden, Zelensky and … … There is also a Zelensky? "

　　Video screenshot

　　Recently, a video shot by Polish media Fakt "stirred up a thousand waves with one stone" on social media. In the video, US President Biden and Ukrainian President Zelensky walk on a flight of stairs, while a man who looks very similar to Zelensky appears in the background.

　　Zelensky’s secret body double is exposed? The identity of this man has caused countless speculations.

　　We are inseparable and have been in the same box for many times.

　　Short crew cut, beard, T-shirt … … At first glance, this man is really indistinguishable from Zelensky.

　　But in fact, this "mystery man" is not a "secret body double", but Maxim Donets, Zelensky’s personal bodyguard.

　　According to the Ukrainian Independent News Agency, Donets was born in Krivorog, Dnepropetrovsk, and graduated from Krivorog School of Economics, Kiev State University of Economics.

　　Screenshot of Ukrainian Independent News Agency report

　　According to foreign media, in February 2019, when Zelensky started to participate in the Ukrainian presidential election, Donets served as his bodyguard. Before that, Donets was the personal bodyguard of Ukrainian billionaire Igor Colomo Isky.

　　In May 2019, after Zelensky became Ukrainian president, Donets was appointed as the head of the president’s personal bodyguard team. Since then, Donets has always been inseparable from Zelensky, and has been in the public contract box many times, including when Biden made a surprise visit to Kiev last week — — He is always observing carefully whether the environment around Zelensky is dangerous.

　　There are many bodyguards in Zelensky, but Donets is particularly concerned because of his excellent appearance. Netizens think he is "very handsome" and "very attractive".

　　Screenshot of foreign media reports

　　A reporter from the British Broadcasting Corporation (BBC) who specializes in investigating false information quipped: "Zelensky’s ‘ Body double ’ He doesn’t look like him at all. He just (generously) walked behind the president’s right and walked in front of the camera. "

　　They all have "body double"?

　　"There are four Bidens in the United States and two Zelensky in Ukraine (also normal)."

　　Zelensky’s "body double Oolong" also triggered a wider discussion among netizens about the "body double" problem of important people.

　　Some netizens commented: "Senior politicians and celebrities generally have body double."

　　Snopes, an American fact-checking website, said that in addition to Biden, netizens had posted "evidence" that US Vice President Harris and former First Lady and Trump’s wife Melania Trump also had body double.

　　Sputnik news agency & radio once quoted Valery Maliwani, a secret service historian, as saying that many world leaders have body double, which is the traditional "internal match" of presidential security secret services.

　　According to him, former US President Trump has three body double’s, and so does Israeli Prime Minister Benjamin Netanyahu.

　　The official Russian news agency Tass once asked Russian President Vladimir Putin whether he was "himself", and Putin gave a positive answer. It is reported that Putin also admitted that he had been suggested to use body double in public places to ensure safety, but he rejected the proposal. (End) (Intern Wang Continued Burning)

　　At present, Aouita has built its own moat in the field of intelligence, with the joint help of Changan Automobile, Huawei and Contemporary Amperex Technology Co., Limited, and there is only one brand that Huawei really participates in the R&D, production and supply, that is, Aouita and Aouita have created a new world of their own in the field of intelligence, and the first model Aouita 11 has been listed, which is regarded as the embodiment of wisdom in the automobile industry. Taking advantage of the trend, positioning the new high-end intelligent coupe GT model Aouita 12 is also coming to us.

　　This is the official preview of Aouita 12, and it is also the declaration map in the declaration information of the 374th batch of new cars. The design of the vehicle continues the maverick of Aouita brand. Headlights mainly with light bands have the effect of being surrounded by abnormity, and we can also see the coupe design with convex sides and concave center in the engine compartment. The lower air intake grille will lower the visual center of gravity of the vehicle, and the annular enclosure formed by the headlight group passes between the lower grille and the front bumper, which has become one of its personality symbols.

　　Aouita 12 has a long wheelbase of 3020mm, a body of 5020mm and a width of 1999mm. In the rear design, the tendency of the vehicle’s hatchback is still very obvious, but because the vehicle actually uses a panoramic canopy to combine the roof structure with the rear windshield, it is closer to the sliding back in the tailgate style, which is more smooth and coordinated than the Krypton 001.

　　As an intelligent vehicle, Aouita’s most outstanding performance is naturally its intelligent driving. In terms of power, Aouita 12 will continue to be equipped with Huawei DriveONE drive system, and provide two power specifications: rear rear drive and front and rear dual-motor four-wheel drive. The power parameters of the front and rear motors are 195 kW/280 N m and 230 kW/370 N m respectively, which are completely consistent with Aouita 11. Under the same level of dynamic parameters, coupled with the low drag coefficient brought by the coupe modeling, it can be seen that Aouita 12 has stronger data performance on the performance output level.

　　Aouita 12 had the only electronic exterior rearview mirror that was legally put on the road in China before the project. According to the Performance and Installation Requirements of Indirect Vision Devices for Motor Vehicles issued last year with the national standard number of GB15084-2022, this kind of rearview mirror has been recognized. At present, Aouita 12 has also become the first and only model successfully declared and mass-produced in China. Compared with the traditional rearview mirror, this design is better in both the blind spot and the adjustment mode.

　　Aouita has achieved an all-round lead in intelligent driving and other aspects. In this context, the strong launch of Aouita 12 is certainly not bad. As for what glory it can create in the future, let us wait and see.