最新上海贵族宝贝自荐区

Photo courtesy of Tibet Forestry and Grass Bureau of Puruogangri Glacier in Qiangtang National Park Creation Area

Tibet is an important national ecological security barrier, with almost all types of terrestrial ecosystems. Protecting Tibet’s ecological environment is beneficial to the future and the world.

Tibet has included all the areas with the most important ecosystem, the most unique natural landscape, the most essence of natural heritage and the richest biodiversity into the candidate areas of national parks. These areas are also the carriers of the national ecological security pattern of "two screens and three belts" and the important ecological protection and restoration projects of "three areas and four belts", which are of great significance for building the ecological barrier of the Qinghai-Tibet Plateau, protecting the ecological security of China, even Asia and even the world, coping with climate change and protecting biodiversity.

Photo by Peng Jiansheng, a national first-class key protected wild animal.

The uniqueness of Tibet National Park

The candidate areas of Tibet National Park include the world’s highest peak and the most spectacular extremely high mountain group, the largest and deepest canyon, the world’s largest glacial action center except the North and South Poles, the largest alpine desert and alpine grassland, the inland plateau lake with the largest number of lakes and the highest lake elevation, the most developed permafrost area in the middle and low latitudes of the northern hemisphere, and the most unique natural landscape and the most essential natural heritage.

These areas are the core distribution areas of rare and endangered protected species such as Tibetan antelope, wild yak and snow leopard, which have the largest number of wild populations and the richest genetic diversity in the world. They are the gene bank of plateau species, one of the key hotspots of biodiversity conservation in China and the world, and have a very important position in the global alpine biodiversity. These areas are also the unique cultural protection sites of the Chinese nation, and they are the demonstration and inheritance sites of snow culture in the Qinghai-Tibet Plateau and the model of harmonious coexistence between man and nature.

Photo courtesy of Tibet Forestry Bureau of coniferous and broad-leaved mixed forest in Gaoligongshan Mountain

Construction of Tibet National Park

Attach great importance to it for a long time. In 2014, Tibet started basic work such as scientific investigation and resource investigation in the areas of Mount Everest and Qiangtang. In 2021, the Tenth Party Congress of the Autonomous Region proposed to "strive to build two national parks, Mount Everest and Qiangtang, consolidate the good momentum of developing one of the regions with the best ecological environment in the world, and strive to make the construction of ecological civilization at the forefront of the country". Wang Junzheng, secretary of the Party Committee of the Autonomous Region, has successively given instructions such as "actively promoting the construction of Qiangtang National Park, effectively protecting the source of rivers and the water tower of Asia", "deepening the construction of Mount Everest National Park, strengthening the protection of glaciers" and "accelerating the construction of national parks such as Tangbei area of the Three Rivers, Qiangtang and Mount Everest". Tibet has vigorously promoted the construction of national parks, and all work has been comprehensively promoted. At present, the construction of Sanjiangyuan National Park is accelerating, and the candidate areas of Qiangtang and Everest National Parks have been approved by the national reply.

Top-level design, multi-party promotion. Organized and compiled the Demonstration Report of roof of the world National Park Group in Tibet, made the Decision on Establishing a National Demonstration Zone for Ecological Civilization Construction and Accelerating the Construction of Beautiful Tibet, promulgated the Regulations on Ecological Civilization Construction in Xizang Autonomous Region, and issued a series of institutional documents such as Xizang Autonomous Region’s Implementation Opinions on Establishing a Nature Reserve System with National Parks as the Main Body. With the cordial care of the CPC Central Committee and the strong support of the relevant state departments, the administrative areas of Qinghai Province and the areas related to the actual use and management of Xizang Autonomous Region, north of Tanggula Mountain, were included in the scope of Sanjiangyuan National Park, and the mechanism of "unified planning, unified policies, separate management and separate responsibility" was innovatively implemented in the two provinces of Qinghai and Tibet, which greatly promoted the implementation of the overall ecological protection, system restoration, comprehensive management and ecological enrichment project in this region.

Protection first, system governance. The tenth Party Congress of the autonomous region proposed to establish a nature reserve system with national parks as the main body and increase the protection of forests, wetlands and grasslands. Tibet adheres to the integrated protection, restoration and systematic management of mountains, rivers, fields, lakes, grass, sand and ice, strengthens the protection of important river sources and key river basins such as the Yangtze River, the Yarlung Zangbo River and the Nujiang River, maintains the authenticity and integrity of the key protected wildlife distribution areas such as Tibetan antelope and wild yak in China, implements the withdrawal of regional mining rights, and strengthens the management of the ecological environment, which has greatly promoted the protection of biodiversity in the Qinghai-Tibet Plateau.

Government-led, diversified investment. The finance of the autonomous region has arranged a total of 500 million yuan to build 92 high-standard management stations in Qiangtang and Everest, employ 930 professional managers of farmers and herdsmen, and arrange 50 million yuan for monitoring, supervision and ecological management every year. Guangdong Changlong Group donated 100 million yuan in five years, and successively implemented the capacity improvement projects of Tibet Tibetan Antelope Research Center and 73 management stations in Qiangtang Nature Reserve. Tibet Amacang Foundation has equipped 780 professional managers of farmers and herdsmen in Qiangtang with winter patrol clothes. Vanke Public Welfare Foundation has invested more than 10 million yuan to carry out snow leopard monitoring in Mount Everest Reserve. The autonomous region has also implemented a series of major projects, such as returning grazing to wild areas, ecological environment protection and restoration, wetland protection and restoration, compensation for damage caused by wild animals, improvement of wildlife habitats, and establishment of ecological poverty alleviation posts, and gradually formed a government-led and multi-party fund investment mechanism for national park construction and management, which has achieved positive results.

Innovate means and strengthen monitoring. Tibet cooperated with a number of scientific research institutes and adopted advanced technical means. Over the past 10 years, more than 500 people went deep into Qiangtang area for 24 times, wearing 15 sets of satellite tracking collars, installing 2 sets of high-definition intelligent spherical cameras and more than 200 infrared cameras for Tibetan antelope population. The preliminary study revealed the migration law of Tibetan antelope in Qiangtang. The largest delivery room of Tibetan antelope was found, with a population of more than 100 thousand; The drone photographed 60,000 Tibetan antelopes migrating. For the first time, snow leopard monitoring and research were jointly carried out in Everest Nature Reserve, and the continuous monitoring time was 6 years. The survey results show that the suitable habitat area of snow leopards in the candidate area of Mount Everest National Park is about 11,100 square kilometers, and the estimated number of snow leopards is 106-114. In the candidate areas of national parks such as Qiangtang and Everest, scientific research monitoring and evaluation were first carried out.

Pay attention to the platform and increase publicity. Tibet has cooperated with mainstream media such as CCTV to carry out a large-scale scientific research report on "We and Tibetan antelope" for 10 consecutive years, and presented the scene of Tibetan antelope migration and calving to the world audience by more than 200 live broadcasts and recordings. In cooperation with Beijing Forestry University, Vanke Public Welfare Foundation, etc., China introduced the multi-party cooperation mechanism between reserve management bureau, public welfare foundation and scientific research team in snow leopard protection at international snow leopard protection academic conferences such as Kazakhstan and Kyrgyzstan, and global snow leopard and ecosystem. Many times in the "International Snow Leopard Day" public welfare publicity activities, the achievements and progress in the protection of snow leopards on Mount Everest were introduced, and publications such as Little Snow Leopard: Friends of Snow Mountain and Mount Everest: Little-known Secret of Life were published.

Tibetan antelope Xinhua News Agency reporter Jue Guo photo

The future of Tibet National Park

Improve the political position and gather together the national ecological protection strategy. The autonomous region regards the construction of national parks as "the biggest in the country", and as an important part of the construction of ecological civilization, it strives to make Tibet’s contribution to safeguarding the ecological security of the country, protecting the roof of the world, the water tower of Asia, the roof of the world of the earth, and building a national ecological security barrier.

Focus on protection objectives and establish and improve the ecological system. According to the functional orientation, protection objectives, management principles and management subjects of national parks, study and formulate laws and regulations that are compatible with national park laws and regulations, combined with reality, and matched with protection and management tasks, so as to provide institutional guarantee for ecological protection, construction management and ecological enrichment of national parks.

Innovate the development mechanism and gradually realize standardization. Adhere to the principle of natural restoration, give necessary artificial promotion, strengthen the protection site, patrol road network, monitoring and control, emergency relief, forest and grassland fire prevention, pest control, wild animal epidemic monitoring, prevention and control, protection and management facilities construction, establish and improve high-tech monitoring means, promote the informationization and intelligence of protection patrol monitoring, and gradually realize standardization and standardization.

Based on protection and construction, vigorously implement the ecological enrichment project. The candidate areas of national parks in Tibet are located in glacier snow-capped mountains, river headwaters, lakes and marshes, grassland forests, Gobi deserts and areas rich in animal and plant resources. These places are difficult in conditions, location and development. Combined with the construction of national parks, people who have the ability to work will be transformed into ecological rangers on the spot and get paid for their work in ecological protection. Adhere to the ecological protection first, coordinate the relationship between protection and development, moderately carry out eco-cultural tourism, let the people eat eco-food and embark on the road of getting rich in participating in ecological protection construction, and realize the unity of ecological protection, green development and improvement of people’s livelihood.

Innovate the construction mode and continuously enrich the connotation of ecological aid to Tibet. Tibet’s national parks are expected to rank among the top in the country. In addition, Tibet’s harsh natural environment, lack of talents and backward technology have shortcomings and weaknesses in fulfilling the responsibilities of ecological protection and restoration, supervision and management, scientific research and monitoring, and publicity and education of national parks. Exploring and expanding the new mechanism of group aid to Tibet, and effectively increasing the introduction of talents and counterpart support will help to further accelerate the construction of national parks in Tibet, which is of great practical significance for making national parks an important strategic place to build a national ecological security barrier, an important demonstration place to achieve harmonious coexistence between man and nature, an important experimental place to promote green development, an important exhibition place to highlight nature protection, and an important pioneer place to realize ecological enrichment. (Zongga)

Photo by Dong Lei, a national first-class protected wild animal, the brown-tailed rainbow pheasant.

On December 18 th, according to the "Late Auto" report, Tesla Shanghai Factory is about to usher in two new models, both of which are Model Y series. One is the modified Model Y that will be mass-produced next month, and the other is the six-seat Model Y that is expected to be delivered in the fourth quarter of 2025.

The redesigned Model Y will learn from the new design concept of Model 3 Huan, and comprehensively improve the interior and exterior decoration, battery capacity, motor performance and autopilot kit. In terms of appearance, the new car will adopt a front face design similar to Model 3, and the LED headlights will be connected by light strips to form a unique penetrating effect, making the front of the car more concise. The side still maintains the classic shape of the coupe SUV, equipped with black double five-spoke wheels, while the tail is highlighted by the penetrating taillights.

According to Tesla’s past practice, before the new models go on the market, the old models usually launch discount promotions. At present, Tesla Model Y has launched a preferential activity of reducing the final payment by 10,000 yuan. For consumers who are ready to buy a car, it is necessary to carefully weigh whether to choose the old one or wait for the new one.

As for the six-seat Model Y, it is the first time Tesla has launched a six-seat model in the China market. However, Model Y, which is currently on sale, has a body length of only 4,750 mm and a wheelbase of 2,890 mm, and is an entry-level medium-sized SUV in the domestic market. If the six-seat Model Y forcibly adopts the three-row six-seat layout without lengthening the body, the legroom and ride comfort of the third row may be affected to some extent. Consumers need to expect this when purchasing.

The new model plan of Tesla’s Shanghai factory shows its continuous attention and investment in the domestic market, and it is expected that these two new models will bring more choices and better driving experience to consumers.

　　[News] On September 9, 2015, Auto officially opened the newly-built China R&D headquarters in Jiading, Shanghai, and laid the foundation stone for the Asia-Pacific headquarters of Volvo Car Group. The opening of Volvo Car’s R&D headquarters in China will not only enhance the overall strength and level of R&D in China’s automobile industry, but also train more automotive technical talents with leading core R&D in the world for China. All senior R&D executives from the Transport Committee of the Swedish Parliament and the headquarters of Volvo Car Group also came to the R&D headquarters of Volvo Car in China to witness this historic moment symbolizing that Volvo’s development in China has entered a new stage.

　　Volvo Car China R&D headquarters is located in Jiading District, Shanghai. The first phase of the project has a construction area of 35,000 square meters and an investment of about 420 million yuan. It consists of vehicle emission laboratory, powertrain laboratory, electronic and electrical laboratory, durability laboratory, active safety and chassis laboratory, indoor air quality laboratory, color matching laboratory, material testing laboratory, salt spray corrosion laboratory, test instrument development laboratory, test preparation workshop, logistics warehouse and engineer office area.

　　R&D scope includes automobile modeling design, interior and exterior decoration design, active safety and chassis design, electronic and electrical system design, powertrain, and new energy and intelligent interconnection technology representing the future development direction of automobile industry. According to Volvo’s global standards and management process, China R&D Headquarters has adopted the industry-leading laboratory layout and equipment, which will comprehensively enhance the R&D capability of China and maximize the synergy with Sweden R&D Headquarters.

"Left: Volvo Asia Pacific S60L Right: Imported"

"Left: Volvo Asia Pacific XC60 Right: Imported"

　　The establishment of Volvo China’s R&D team dates back to 2011. Since its establishment in early 2011, the number of the team has exceeded 500, and it has successfully developed a variety of products for the global market, including XC90, which has just been listed. Since its inception, the R&D team has focused on the R&D and testing of S/V series cars, multi-purpose vehicles and XC series, trying to create products that meet the needs of consumers in China, and at the same time integrating the needs of consumers in China into new products facing the global market.Up to the present position, Volvo China R&D team has completed the following nine important R&D projects, namely:

1. Design, configuration upgrade and localization of 1.S60L (China Extended Edition).
2.S80L (China market extended edition) vehicle model change.
3. Design, configuration upgrade and localization of 3.XC60
4. Localization of
5.2.0 localization of li5p
6. Localization of the new generation 2.0L VEP engine
7. Calibration and matching of new generation VEP engine (2.0L) and gearbox
8. Development and localization of 8.S60L plug-in gasoline models
9. Development and localization of 9.S60 Inscription (exported to the American market)

　　In addition, China R&D team cooperated with manufacturing engineering teams and other departments, participated in the construction of Chengdu and Daqing factories and led the production qualification review of the above two factories and new energy vehicles. At the same time, the center has completed the establishment of Volvo’s supplier system in China from scratch in the past four years, and has developed more than 340 local suppliers (including the production organizations of international suppliers in China), greatly improving their overall quality and management level. At the same time, Volvo also launched the "202020 Strategy" for product development–by 2020, it will only take 20 months for new products based on new platforms to be defined and put into production, andChina’s future product planning and launch will be completely synchronized with Europe.

　　Different from most joint venture brands setting up R&D centers in China,Volvo Car Shanghai R&D Center is a wholly-owned organization, so there is no barrier between the new R&D headquarters and the Swedish headquarters, let alone a firewall.The R&D resources and achievements have been shared globally, and the R&D work has progressed together. Through Volvo’s global unified product development system, China has formed a R&D pattern with the headquarters in Gothenburg, Sweden, which unifies research methods, workflow, standards and equipment.

　　At present, Volvo Cars has put some research and development work on the latest generation of energy-saving and environment-friendly engines and intelligent in-vehicle interactive systems in China. In the future, the focus of research and development work in China will include researching and developing a series of highly competitive products that meet the needs of consumers in China on a brand-new platform, and working with the headquarters to develop a new generation of new energy vehicles. At the same time, the R&D team of China will actively assist the headquarters in the research and development of new generation powertrain technology, active and passive safety technology, intelligent interconnection technology and autonomous driving technology.

"Volvo Asia Pacific S60L T5 Hybrid Model"

　　In addition, with the domestic production of T5 plug-in hybrid products, the team has introduced the latest generation of new energy-saving and emission-reduction engine research and electric drive system platform to China, and made changes according to the China market, so that the diesel hybrid power model originally launched for overseas markets finally has a gasoline model equipped with Drive-E powertrain that is more in line with the demand of China market, which greatly promoted the technical level of China R&D team in powertrain and new energy vehicle development, and laid a sufficient talent base for further research and development of more models in the future. What’s more worth mentioning is that China’s R&D team cooperated with various departments to successfully export the extended version of "Made in China" Inscription to the United States this year, which is also a historic breakthrough in the history of China’s automobile manufacturing.

　　At the same time, the foundation stone was laid for the Asia-Pacific headquarters building of Volvo Car Group, which will be adjacent to the China R&D headquarters building of Volvo Car in the future, with a total investment of about 1.7 billion yuan, with a total area of 38,400 square meters for new buildings and 108,500 square meters for new buildings, with a total area of 300 mu. Upon completion, it will not only become the nerve center of sales, R&D, procurement and production of Volvo Cars in the Asia-Pacific region, but also include the headquarters building with a construction area of about 60,000 square meters, the automobile museum, the design and modeling center, the trial-production workshop, and other laboratories and their auxiliary power facilities that will be built in the China R&D Center.

　　At present, the R&D Center in China has nearly 500 staff members, including 30 experts from Volvo’s Swedish headquarters, 15 overseas senior experts (including 2 specially invited experts from the National Thousand Talents Program) and more than 400 technical R&D engineers (including 14 doctors, 136 masters and 229 undergraduates). With the full development of Volvo Car R&D project in China, the total number of R&D centers in the future will continue to grow rapidly. (Text/Photo/Photo by Huang Zhengqiao, car home)

Extended reading—

Will be exported to the American-made S60 Inscription real vehicle.
//www.autohome.com.cn/news/201505/874222.html

　　21st century business herald reporter Ji Yuanyuan reports from Shanghai Recently, Yixinhe Pharmaceutical Technology Co., Ltd. (hereinafter referred to as "Yixinhe Medicine") developed and produced, and (1) Shakuba Quvalsartan Sodium Tablets (brand name: Yixintan) which was exclusively commercialized was approved by National Medical Products Administration (NMPA). Yixintan is the first generic drug of shakubatravalsartan sodium tablets approved for marketing in the global regulatory market by breaking through the original research patent through innovative crystal forms. The approved indications of this product are for treating essential hypertension and adult patients with chronic heart failure (NYHA II-IV grade, LVEF≤40%) with reduced ejection fraction, so as to reduce the risk of cardiovascular death and hospitalization for heart failure.

　　Immediately afterwards, Unacon also announced that its subsidiary company Shiyao Ouyi developed Shakubatrivalsartan sodium tablets (50mg, 100mg, 200mg) which have obtained the drug registration approval issued by National Medical Products Administration, and regarded them as the adult patients with chronic heart failure (NYHA II-IV grade, LVEF≤40%) with reduced ejection fraction, which reduced the risk of cardiovascular death and hospitalization for heart failure.

　　With the approval of domestic shakubatravalsartan sodium tablets, Novartis, the original drug manufacturer, also released information at the first time, saying that the marketing license for the generic drug of Novartis’ original research product shakubatravalsartan sodium tablets was approved, and Novartis declared that the pharmaceutical active ingredient of the original research product Noxintuo was protected by patents ZL200680001733.0 and ZL201210191052.2 in China.

　　According to the relevant provisions of Article 11 of China’s Patent Law, any enterprise or individual shall not manufacture, use, promise to sell (including applying for online registration, participating in bidding, etc.), sell or import products falling within the scope of the above patent protection before the expiration of the above patent period, otherwise it will constitute patent infringement. To this end, Novartis emphasizes that it will reserve the right to claim its patent right against infringing imitations from relevant judicial and/or administrative organs.

　　Regarding the patent issue, according to the public information, in April 2017, the patent of Shakubatroxobin Sodium Tablets registered by Novartis was declared invalid in China. On July 2, 2021, the crystal patent was also partially invalidated in China. Yixin and Medicine also emphasized in the official disclosure information that in 2022, the domestic sales of Shakuba Quvalsartan sodium tablets totaled nearly 3 billion yuan, and its China patent will expire in November 2026. Yixintan is a first-line drug for the treatment of heart failure and hypertension with independent intellectual property rights, which can legally make the majority of patients with heart failure and hypertension in China use equivalent and affordable innovative drugs three years in advance.

　　It can also be seen that the domestic Shakubatroxobin Valsartan sodium tablets have been approved one after another, which will bring certain market challenges to the original drug.

　　More than 10 pharmaceutical companies compete for the market

　　Shakubatroxobin and valsartan sodium tablets are a new type of eutectic drug composed of enkephalinase inhibitors Shakubatroxobin and angiotensin receptor blocker valsartan sodium tablets in a molar ratio of 1:1. Eutectic structure can make the absorption and elimination rates of shakubarb and valsartan sodium tablets similar, and ensure the synchronous consistency of their efficacy. In addition, compared with independent preparations, eutectic drugs have the advantages of constant composition ratio, good storage stability, and can significantly improve drug solubility and oral bioavailability.

　　As a representative drug of ARNi, Shakubatroxobin sodium tablets have been unanimously recommended by domestic and foreign guidelines in recent years. In 2021, the American Heart Association proposed that ARNi drugs should be given priority to patients with HErEF, and it is recommended to use them to the maximum tolerated dose or target dose (Class I). In 2018, China Heart Failure and Treatment Guidelines also recommended to replace ACEI/ARB with ARNi to further reduce the incidence and mortality of heart failure (Class I).

　　Sakubatravalsartan sodium was originally researched by Novartis Entresto, and was first approved by the FDA in July 2015. It is the world’s first breakthrough and innovative drug in the field of heart failure treatment, and was approved to enter the domestic market for the first time in July 2017. It was included in the national medical insurance category B catalogue through negotiation in 2019, successfully renewed in 2021, and added indications for essential hypertension. In 2021, the global sales of the original research sand kubatroxobin sodium reached US$ 3.548 billion. In 2022, its global sales scale reached US$ 4.644 billion, up 37% year-on-year. In the first half of 2023, the drug also grew into the best-selling drug of Novartis, with sales reaching US$ 2.915 billion, up 31% year-on-year, and it is expected to exceed US$ 6 billion in the whole year.

　　In the China market, the original yanshakubatravalsartan sodium is also a heavy variety. According to the data of the Minenet, the sales growth rate of this product in China’s three major terminals and six major markets has reached triple digits in recent years. In 2021, it exceeded 2 billion yuan for the first time, up 127.62% year-on-year, with full market potential; In 2022, the sales of Shakubatroxobin Sodium Tablets in China’s three major terminals and six major markets exceeded 2 billion yuan. Among them, the hospital market (public hospital terminal+public primary medical terminal) is the main sales channel, with a year-on-year increase of 6.54%.

　　In this regard, some brokerage analysts told 21st century business herald that the innovative product layout must be aimed at chronic diseases, major diseases, diseases that pose a major threat to people’s health, such as cardiovascular diseases, tumors and major infectious diseases. At the same time, the core of making medicine is clinical value. With the rapid development of life science, many interdisciplinary fields are very active, and the large-scale treatment methods focusing on large populations are worthy of attention.

　　"The successive approval of domestic shakubatravalsartan sodium tablets is a great benefit for cardiovascular patients, although the layout of many domestic pharmaceutical companies is already in the clinical stage, except for the single-minded and pharmaceutical/Fosun Pharma, Shiyan Ouyi, including Sichuan Kelun, Chengdu Beite, Qilu Pharmaceutical, Zhengda Tianqing, etc. are also accelerating the layout. This is due to the accelerated layout of many domestic pharmaceutical companies, and the prices of related products are expected to be further lowered, eventually benefiting more patients. " The above analyst said.

　　According to the data of Minenet, at present, there are three companies that have production approval documents for Shakuba Quvalsartan Sodium Tablets. Among them, Unacon Ouyi Pharmaceutical Co., Ltd. and Nanjing Yixin and Medical Science and Technology Co., Ltd. were all approved on the same day with four types of imitation, which are regarded as over-evaluation, and tied for the first imitation and the first over-evaluation. In addition, 17 enterprises, including Shandong New Times Pharmaceutical, Nanjing Zhengda Tianqing Pharmaceutical and Qilu Pharmaceutical (Hainan), all reported their production under the new classification.

　　An unavoidable patent dispute

　　The competitive anxiety between Chinese and foreign pharmaceutical companies in Shakuba Quvalsartan sodium tablets is also considered to be an important reason for patent confrontation. At the same time, in recent years, patent disputes between original drugs and generic drugs have occurred from time to time. 21st century business herald reporter found through the search of Wisdom Bud database that as of the latest, there are more than 700 drug patents with litigation results in China, and more than 99% of them are invention patents. It can be seen that the handling of drug patent disputes needs urgent attention.

　　Yixinhe Medicine also emphasized in the official information disclosure that Yixintan is a first-line drug for the treatment of heart failure and hypertension with independent intellectual property rights. Compared with the reference crystal form, when the relative humidity changes from 20% to 60%, it absorbs less water and is more stable, and can be sealed and stored below 30℃. This stable crystal form is more suitable for the vast China market.

　　When talking about patents, some pharmaceutical executives also told 21st century business herald that the research and development of original innovative drugs has always been a "three high" industry with high threshold, high risk and high return. According to the latest literature, it takes an average of 12.5 years for a new drug to go on the market, which costs nearly $2.6 billion, and the success rate is less than 10%. Every new drug project is the most important decision of an enterprise, and the project process needs a lot of data research, especially the research on patents, documents and regulations takes a lot of time.

　　"Therefore, how to find a balance between ensuring the innovation enthusiasm of the original drug research enterprises and reducing the burden on patients has been hotly debated. The FDA’s definition of generic drugs is very strict, and the requirements must be consistent with the dosage form, specifications and administration route of the copied products. If it is inconsistent, it will be declared as a new drug. " The above-mentioned pharmaceutical company executives said that for the long-term public interest, the state needs to protect the enthusiasm of the original drug research and development enterprises. At the same time, in order to limit the original drug research and development enterprises, it is necessary to encourage the imitation research and development of the original drug from the level of institutional norms and ensure the interests of generic drug enterprises.

　　In order to better balance the interests of the original research drug and generic drug companies with the system, the new Patent Law, which came into effect on June 1, 2021, established the drug patent linking system in China, aiming at linking the two legal procedures, so as to clarify the interest relationship between the original research drug manufacturers and generic drug manufacturers and avoid the problem of patent punishment when the generic drug research and development is completed.

　　As for how enterprises can avoid patent risks, Hou Xuchao, the founding partner of CIC Consulting, also told 21st century business herald that from the perspective of investment and financing, pharmaceutical companies have five key parameters when choosing product pipelines, including the success rate of products under research, patient base, product penetration rate, product pricing and patent life. With the improvement of pharmaceutical companies’ R&D strength, patent life needs more and more attention.

　　"For the patent situation of unlisted drugs, investors need to hire professional IP lawyers to conduct detailed investigations. Because patent conflicts will directly make it difficult for candidate drugs to be marketed, and even directly affect the product value measured by all the above parameters, it is an essential step for patent investigation. " Hou xuchao said.

　　There is a huge crowd in the chronic disease market behind Shakuba Quvalsartan sodium tablets. In terms of hypertension alone, China, as a big country with hypertension, has 245 million adult hypertensive patients, which means that Shakuba Quvalsartan sodium tablets have a broad market space and are an important direction for the future development of drugs. I believe many domestic and foreign manufacturers will make layouts and list related products one after another.

　　However, it should also be noted that after the appearance of the first imitation drug, the clinical data, approval time and product price of the follow-up drugs and enterprises will all be factors affecting the competition pattern, especially the clinical effectiveness and safety, which will be the key to decide who can go further in this track.

Knock on the door of the future with the question of youth; Respond to the world focus with the answer of youth. On October 25th, the online theme communication ceremony of "Chinese modernization, youth’s answer-I know you better than ever (the third season)" was held in Changzhou, Jiangsu. Yang Liqun, Vice Minister of Propaganda Department of jiangsu provincial party committee and Director of Network Information Office of Provincial Party Committee, Li Zhenqiang, Deputy Secretary and General Manager of Phoenix Publishing Media Group, Liu Wei, Deputy Director of Network Information Office of jiangsu provincial party committee, Chen Zhiliang, member of Standing Committee of Changzhou Municipal Committee and Minister of Propaganda Department, heads of relevant departments such as Jiangsu Provincial Committee of the Communist Youth League and Changzhou City, heads of provincial key online media, central news websites and commercial platforms in the Soviet Union, Qingqing "Answers" and representatives of young volunteers of network civilization attended the launching ceremony.

Yang Liqun, deputy director of the Propaganda Department of jiangsu provincial party committee and director of the Network Information Office of the Provincial Party Committee, pointed out in his speech that planning to launch a series of short videos of "Chinese modernization, youth’s answers-I know you better than ever (the third season)" is a powerful measure to deeply study the cultural thoughts of the supreme leader, implement the spirit of the national conference on propaganda and ideological work and the national conference on online information work, and also a practical action to accelerate the construction of digital China and promote Chinese modernization with the power of online information and youth. Yang Liqun stressed that it is necessary to hold high the ideological banner and use the Party’s innovative theory Bacon to cast souls. In particular, it is necessary to teach the online "Great Ideological and Political Course" in the new era, empower young people with digital ideological and political guidance, and cultivate new people in the era who are responsible for national rejuvenation. It is necessary to increase the spread of positive energy, use high-quality content to cultivate the power of upward goodness, and win the communication advantage with the content advantage of "full screen is fine". We should be good at innovation, use emerging technologies to crack the traffic password of explosive products, and realize the "two-way trip" with netizens. It is necessary to focus on the all-media ecology, promote the surge of positive energy with integrated communication, continuously expand the new generation of network communication, and jointly tell the story of Chinese-style modernization of youth struggle.

Li Zhenqiang, deputy secretary of the Party Committee and general manager of Phoenix Publishing Media Group, said in his speech that on the basis of the achievements and experience of the previous two seasons, the third season of "I know you better than ever" focused on high-level scientific and technological self-reliance, agricultural modernization, cultural self-confidence and high-level opening up, and went to 23 cities across the country to shoot and produce a series of 30 short videos, which fully demonstrated the vivid practice of promoting Chinese modernization under the guidance of Socialism with Chinese characteristics Thought, the supreme leader in the new era. Li Zhenqiang pointed out that Jiangsu Phoenix Publishing Media Group will thoroughly implement the spirit of the important instructions of the Supreme Leader General Secretary, give full play to the comprehensive advantages of Phoenix Group in content production, integrated publishing and international communication in accordance with the deployment requirements of the Propaganda Department of jiangsu provincial party committee and the Network Information Office of the Provincial Party Committee, support Modern Express to accelerate the construction of a new pattern of all-media communication with more communication power, guidance, influence and credibility, and make new and greater contributions to serving local economic and social development and helping the new practice of Chinese modernization in Jiangsu.

Chen Zhiliang, member of the Standing Committee of Changzhou Municipal Committee and Minister of Propaganda Department, said in his speech that at present, Changzhou is making every effort to sprint "a city with a trillion GDP", striving to build a city that young people are most eager for innovation and entrepreneurship, and launching a series of inclusive policies and practical projects to optimize youth development, so that young people and Changzhou can "go in two directions and build their ideals together". Chen Zhiliang said that "I know you better than ever (the third season)" was officially launched in Changzhou, allowing young people to stand in the "C position" of network communication, allowing more young people to come to the front desk, relay positive energy, and unite hundreds of millions of young people to unswervingly listen to the party and follow the party. Changzhou will take the event as an opportunity to gather the forces for good and upward, and join hands with the vast number of netizens to build a beautiful spiritual home online.

In order to thoroughly study, publicize and implement Socialism with Chinese characteristics Thought of the Supreme Leader in the New Era and the spirit of the 20th Party Congress, and strengthen the ideological guidance for young people, from 2021 to 2023, under the guidance of the Network Communication Bureau of the Central Network Office, the network theme publicity of "I know you better than ever" was produced by the jiangsu provincial party committee Network Office of the Communist Party of China and produced by Modern Express+. The short video of the three seasons takes the form of "youth talking to youth", so that "young people can talk" and "talk to young people".

In the first two seasons, in the first season, 30 Qingqing narrators from 30 universities across the country participated, in the second season, 30 big coffees served as top flow recommendation officers, and 30 Qingqing study groups crossed 30 cities to explore the road of Chinese modernization. In the third season, Xiaoqing, the anchor of AI digital man developed by Modern Express+,invited 30 outstanding young people from all walks of life and fields across the country who were struggling in the front line of Chinese modernization as Qingqing "Answers", and went to 23 cities in 13 provinces (autonomous regions and municipalities) all over the country. After nearly half a year, they carefully planned and filmed, witnessed the fiery practice of Chinese modernization and showed the surging power of contemporary youth to participate in Chinese modernization.

At the launching ceremony, as the representative of Qingqing’s "Answer" person, Long Jing, director of canoe Zhihang Operation Management Center, took the stage to speak, and reunited with AI digital person Xiaoqing to share their wonderful stories.

Mo Yi, the chief R&D engineer of Trina Solar Co., Ltd., who is one of the hosts of the live event, is a post-90 s returnee. She also participated in one episode as an "answer" person of Qingqing, and punched in a online celebrity parking lot in Changzhou Zhonglou District during the filming.

In the process of creating the three-season series of short videos of "I know you better than ever", nearly 200 outstanding young people from major universities and industries in China gathered. They answered the questions of youth with their youth and blood, shouldered the responsibility of youth, and built a youth community with positive energy. Together with the young people in Qian Qian who have devoted themselves to the fiery practice of Chinese modernization, they have jointly constructed a matrix of Chinese-style modernization youth spread through the Internet. Li Chenrui, a member of the Bell Tower, a young volunteer of network civilization in Changzhou, shared the fruitful results of Changzhou’s efforts to promote the construction of the network civilization demonstration belt of the Grand Canal, and called on the vast number of young people to do their best to contribute their youth to the dream of becoming a network power.

Yang Liqun, Vice Minister of Propaganda Department of jiangsu provincial party committee and Director of Network Information Office of Provincial Party Committee, Li Zhenqiang, Deputy Secretary and General Manager of Phoenix Publishing Media Group, Liu Wei, Deputy Director of Network Information Office of jiangsu provincial party committee, Chen Zhiliang, Standing Committee Member of Changzhou Municipal Committee and Minister of Propaganda Department, Shen Dong, Secretary of Changzhou Zhonglou District Committee, and Jiang Yutao, Deputy Minister of Propaganda Department of Changzhou Municipal Committee and Director of Network Information Office, jointly launched "Chinese Modernization: I Know You Better than Ever (Season 3)", and a series of 30 short videos will be released one after another.

The launching ceremony was guided by the Network Communication Bureau of the Central Network Information Office, hosted by the jiangsu provincial party committee Network Information Office of the Communist Party of China, undertaken by Modern Express+,Changzhou Municipal Network Information Office, Changzhou Zhonglou District Committee and Changzhou Municipal Committee of the Communist Youth League, and supported by the Propaganda Department of Changzhou Zhonglou District Committee, Zhonglou District Committee Network Information Office and the Communist Youth League Zhonglou District Committee.

CCTV News:The second season of "Ding Luo Long Dong Choke" will be launched at 19: 30 on September 16th, and will be replayed at 22: 30 on CCTV-1 comprehensive channel and 20:30 on CCTV-11 drama channel that night.

Hui Minli, the quiet partner of the sincere goddess who loves Shaanxi opera.

There is a "contradiction" between tranquility and Hui Minli, a performance artist of Shaanxi Opera. Quiet practices lying fish outdoors in high temperature. When you feel tired, your arm is just about to be put down. Teacher Hui on the side sternly "reprimands" Quiet not to be lazy. Quiet sigh: "Mr. Hui is so fierce. He stressed several times that he has special circumstances and is not suitable for sitting often. I found that I am still suitable for being a teacher and not suitable for being a student."

Quiet partner, Qin Opera performance artist Hui Minli

Comedy big coffee Song Xiaobao partnered with Xiong Zhuying, the storyteller of northern Shaanxi

As an out-and-out Northeastern, Song Xiaobao came to northern Shaanxi to live and eat with Xiong Zhuying’s family, and felt the charm of northwest culture. He shouted: "Shanxi and Shaanxi are stupid and confused, and there are gullies everywhere. It is very difficult for me to jump into the ravine." When communicating with Xiong Zhuying about Errenzhuan and storytelling culture in northern Shaanxi, Song Xiaobao confessed that the reason why "Haiyan, you can grow up" was because you forgot the words.

Song Xiaobao partnered with Xiong Zhuying, the storyteller of northern Shaanxi.

Tiger Hu, a creative genius, partnered with Zhang Jianmin, the inheritor of Huayin old tune.

Tiger Hu was the first star to be exposed in the second season of Ding Luo Long Dong Choke, especially her partner inheritor’s interpretation of Huayin old tune, which inevitably made people compare it with Sitar tan’s performance of "Huayin old tune" which blew up the audience in CCTV Spring Festival Evening. However, Tiger Hu said: "I feel particularly honored that Huayin Laoqiang was the first to know about it, but I didn’t know much about it. Later, Sitar tan performed at the Spring Festival Evening, and now he knows more and more about Huayin Laoqiang. This time, he went to Shuangquan Village to learn from Teacher Zhang Jianmin. I think it is very tasteful, and I think it is something in the bones, very powerful and very energetic. "

Tiger Hu partnered with Zhang Jianmin, the storyteller of northern Shaanxi.

Aestheticism singer Alan partnered with Haidong Lu, the fifth generation inheritor of Lu Pai Suona after 90.

Alan visited Xunyi and followed Haidong Lu, the inheritor of the 1990s, to learn to play suona in the cornfield. When exchanging their hard experiences in learning musical instruments with Haidong Lu, he said, "Learning musical instruments is very hard, others played when I was a child, but I practiced for two or three hours, which was actually very common when I was a child. My parents forced me to learn, and sometimes when my parents were not paying attention, I set the alarm clock up for half an hour, or played it again with a repeater, pretending that I practiced very hard. However, Haidong Lu wants to learn by himself. It is really not easy to be so young and still be able to persist hard. " During the recording, it coincided with Alan’s birthday. Without her prior knowledge, Haidong Lu’s family also prepared a birthday cake and a happy birthday song for Alan, and Haidong Lu’s mother even made a pair of cloth shoes for Alan herself, which promoted her righteousness step by step.

Alan partner suona inheritor Haidong Lu.

　　Xinhua News Agency, Shenzhen, November 10th-The high-level forum of the International Museum was held in Shenzhen, Guangdong Province on the 10th. The top leader of president sent a congratulatory letter to the forum, and Vice Premier Liu Yandong of the State Council read the congratulatory letter and delivered a speech at the opening ceremony.

　　Liu Yandong pointed out that it is of great significance to hold the forum on the occasion of the 70th anniversary of the entry into force of the UNESCO Charter. The congratulatory letter from the Chairman of the Supreme Leader fully reflects that China attaches great importance to the cause of museums, which will certainly encourage and promote international exchanges and mutual learning in the field of cultural relics and contribute to the progress of human civilization.

　　Liu Yandong emphasized that China has thousands of years of civilization inheritance, and its rich cultural heritage bears the cultural genes and spiritual symbols of the Chinese nation. China regards the development of museums as a national cultural strategy, optimizes its layout and improves its functions, thus forming a diversified museum system. The number of registered museums is 223 times that of new China in 1949, with more than 20,000 exhibitions and 700 million visitors every year. Museums are not only institutions that collect, protect, research and display cultural heritage, but also cultural services and educational institutions that serve people’s all-round development and face the future, and have played an active role in economic and social development.

　　Liu Yandong pointed out that it is a common task for all countries to build, protect and make good use of museums. We should enhance the sense of community of human destiny, implement the relevant initiatives of UNESCO, deepen exchanges and cooperation in the fields of exhibitions, cultural relics protection, personnel training, application of scientific and technological achievements, and cracking down on cultural relics crimes, so that countries can enrich their collections and show greater value in the inheritance of civilization and the exchange of people’s hearts.

　　The International Museum High-level Forum was jointly organized by UNESCO, China National Committee for UNESCO, National Cultural Heritage Administration and Shenzhen Municipal Governments, and attended by more than 200 world-renowned museum leaders and experts.

　　The United States is the initiator of the Russian-Ukrainian conflict and continues to profit from it. The United States increased its sanctions against Russia, which made its European allies pay for it, while taking advantage of it.

　　The United States makes "energy wealth" and Europe suffers from high natural gas prices.

　　EU countries were highly dependent on Russian energy, and about 30% of imported crude oil and 40% of imported natural gas came from Russia.

　　After the outbreak of the conflict between Russia and Ukraine, the United States pressured European allies to impose sanctions on Russia, trying to cut off the energy links between Russia and European countries, and turned the energy demand to the United States in an attempt to make an "energy fortune".

　　On March 25, the United States and the European Union launched an energy cooperation plan, which will expand the export of liquefied natural gas from the United States to the European Union. According to the data of Luft Company, a data provider of American financial market, in the past March, the export of liquefied natural gas in the United States was about 7.43 million tons, an increase of nearly 16% from the previous month and a record high. Among them, Europe has become the largest export destination of liquefied natural gas in the United States for four consecutive months, accounting for about 65% of American exports.

　　However, the transportation and storage costs of liquefied natural gas (LNG) from the United States to Europe are higher, and the construction of related facilities is complicated, which can not fully meet the demand of Europe. European countries can only bear the skyrocketing natural gas prices.

　　Europe’s reduction of Russian oil imports has caused oil prices to soar.

　　Russia is the second largest oil exporter in the world after Saudi Arabia. After the outbreak of the conflict between Russia and Ukraine, European countries imposed sanctions on Russia, which led to a decrease in oil supply from Russia. Gunnvor Group, an energy trading giant, warned that if Russian oil supply continued to decrease, Europe would face an "extreme shortage" of oil, which led to a sharp rise in oil prices.

　　However, the United States continues to profit from it and imports a lot of Russian oil. Popov, Deputy Secretary-General of the Russian National Security Council, said on the 3rd that the volume of oil imported by the United States from Russia increased by 43% in the last week, reaching 100,000 barrels per day.

　　American military-industrial complex makes use of European security dilemma to make "war money"

　　In addition, the Russian-Ukrainian conflict has caused European countries great anxiety about European security. It is difficult for Europe to get out of the security dilemma and can only increase investment in national defense. On March 27th, the German government announced that it would increase the defense fund by 100 billion euros, raising the defense expenditure to more than 2% of GDP. Not surprisingly, this big piece of "fat meat" should mainly fall into the mouth of American arms giants. Since the situation in Ukraine became increasingly tense in October last year, the share price of American military giants has risen dramatically and earned a lot of money.

　　At the same time, since the conflict between Russia and Ukraine on February 24, the US dollar has been sought after because of the rising risk aversion in the market. In March, the cumulative increase of the US dollar was 1.7%, and the increase in the first quarter was as high as 2.8%.

　　Peskov: Europe needs to wake up from "American whiskey"

　　Obviously, the United States has strengthened its ties with Europe in military, diplomatic and energy supply through the Russian-Ukrainian conflict. Thierry de Mont Brial, president of the French Institute of International Relations, bluntly said that Europe would suffer more and more from being kidnapped by the United States, and the Russian-Ukrainian conflict once again "made Europe understand the importance of taking its destiny into its own hands and striving for strategic autonomy".

　　Russian Presidential Press Secretary peskov said on the 2nd that Russia-Europe relations are unlikely to improve in the near future. He said that only when Europe "wakes up from American whiskey" and realizes that its own destiny is in its own hands, not the United States, can the relationship between Russia and Europe be repaired.

The national software WeChat once again attracted attention.

On February 3, "WeChat mobile phone number can register two accounts" rushed to the hot search. What do you mean, "WeChat mobile phone number can register two accounts"? Simple understanding is the "trumpet" of WeChat. If you only have one mobile phone number, but want to register two WeChat accounts, it was not possible before, but now you can register two micro signals with one mobile phone number.

For many WeChat users, with more and more WeChat friends, all kinds of friends are concentrated in a micro-signal, which is inconvenient to manage, so many users work under one number and live under one number. As early as 2018, the new function released by WeChat has the function of switching login accounts. However, switching accounts means that you need two mobile phone numbers to register two WeChat accounts.

Many WeChat users feel that this function is a real "epic update". How to register WeChat "trumpet"? What will happen to the new and old WeChat accounts after registration? What should I pay attention to when using it? What convenience can "trumpet" bring?

To register WeChat trumpet, you can do it in WeChat-Me-Settings. Click Switch Account in Settings, and the currently used WeChat account and the prompt of "Add Account" will appear on the page. After clicking Add Account-Register a new account, you can choose whether to register with the new mobile phone number or use the current WeChat mobile phone number to assist in registration.

Of course, the WeChat "trumpet" is registered with the current WeChat mobile phone number. Many netizens said that the WeChat "trumpet" could not be opened for various reasons, for example, the WeChat account without WeChat payment could not be opened, and some netizens encountered the prompt that "there are many people trying to register at present, so you can try again later" when registering. In short, I feel that the current registration function is not stable.

Of course, not all WeChat users can register WeChat "trumpet". There is a certain threshold. According to the official announcement, the conditions for opening WeChat "trumpet" include that the current WeChat account has been bound with the mobile phone number, WeChat payment has been opened, and the registration time has exceeded a certain period of time, and the current account has no security risks.

The step of "auxiliary registration through the current WeChat mobile phone number" is not complicated. According to the prompt, security verification is carried out, including sending a short message according to the prompt, and the user is required to send a short message with the specified content to a specified number with the current WeChat mobile phone number. In fact, the whole registration process is basically this step, and then we need to set the micro signal and login password.

When logging in to this "trumpet" for the first time, WeChat will prompt you to create a micro signal. Be sure to remember that the micro-signal should be set to be easy to remember, because after the registration is completed, the micro-signal "trumpet" will appear in the list of "switching accounts". If you choose to log in with "trumpet", you can’t log in with your mobile phone number as before, but log in by "micro-signal+password". Although you can get it back if you forget the micro-signal, it will be more troublesome.

There is not much difference between using WeChat "trumpet" and using the old WeChat account. The most basic chat, address book and circle of friends are almost the same. There is no data sharing between the WeChat trumpet and the original WeChat account. The friends in the WeChat account are still in the original WeChat account, and the friends in the WeChat trumpet should be added again, which is equivalent to opening a brand-new WeChat account.

However, because there is no real-name authentication, the function of WeChat payment cannot be used in the "trumpet". If you want to open WeChat payment, you need to re-authenticate your real name, that is, you need a mobile phone number for registration authentication.

You don’t need a mobile phone number to register a new WeChat. The WeChat "trumpet" is like a "compressed version". Besides separating work and life to a certain extent, it can also be used by children. Before registering a WeChat account for a child, it was necessary to "consume" a parent’s mobile phone number or set up a new one, which would also bring some inconvenience. Opening a "trumpet" can solve this problem.

Tips：

About WeChat "trumpet", you need to know these.

Q: How many WeChat accounts can a WeChat account assist in registering?

A：What we call "trumpet" is actually to register a new account with an authenticated WeChat account. Each WeChat account can only register one WeChat account, that is, there can only be one trumpet. If you want to register more than one "trumpet", the page will prompt "It is temporarily impossible to register a new micro-signal".

Q: How to let others search for their own "trumpet"?

A：When adding a friend, just tell the other party your own "small" micro signal. If you tell the other party your mobile phone number, the other party will find the original WeChat account.

Q: What should I do if I want to use WeChat payment on the trumpet?

A：You need to bind a new mobile phone number to "trumpet", but it must be a mobile phone number that is not bound to other WeChat, which is equivalent to making "trumpet" an independent WeChat account. Specific operations can be in the "trumpet" I-Settings-account and security-mobile phone number in the binding of a new mobile phone number, go through the identity authentication and other real-name processes.

Q: If you forget the micro-signal and password of the trumpet, how can you get it back?

A: When registering a trumpet, you need to use a mobile phone number to complete a short message verification. This is to ensure the security of the registered account, and this mobile phone number is only used for micro-signal security verification in registration. If there is no "trumpet" bound to the new mobile phone number, you can perform security operations such as login verification and password recovery verification through the old account. If the "trumpet" has been bound with a new mobile phone number, just log in or retrieve the password through the mobile phone verification code.

Q: Many users find it troublesome to switch WeChat accounts. Can I log in to two accounts at the same time after opening the "trumpet"?

A：You think too much about this question, and it is still not possible at present. The two WeChat accounts are relatively independent.

You can have a look

Don’t miss these new WeChat features.

In addition to registering WeChat "trumpet", if your WeChat is upgraded to the latest version 8.0.32, I believe you will find many changes, which is also the first updated version of WeChat in 2023.

1. Add a message prompt when refusing to call.

When I received a voice or video call from WeChat at an inconvenient time, all I could do before was to "refuse". After the rejection, if you want to send a message to the other party, in addition to the reminder of "Call Rejected", a "Send Message" button is added on the message banner of voice or video. Click "Send Message", the page will automatically jump to the quick chat interface, and you can send a message directly to the other party, eliminating the step of going to the friend list to find friends.

2. Support indoor map function

Many "road idiots" have the experience of getting lost in the shopping mall. If you make an appointment to meet your friends in the shopping mall, but you just can’t find the location that your friends said, you can try the indoor map function of WeChat. When sending location or real-time location to friends, the new version can not only send accurate floor location, but also specific to a store. However, at present, only some regions and large supermarkets support this function. If the coverage is getting wider and wider, this function is still very practical.

3. Video playback is scalable

Watching photos on WeChat can be zoomed, but watching videos can’t. Now watching videos and watching photos have "equal treatment". After selecting a video, click "Play Full Screen", and you can pinch or double-click the screen with your two fingers. The video screen will be enlarged or reduced, similar to zooming photos.

4. Customize chat history cleaning

Chat record is the "treasure" of WeChat, which accounts for most of the chat record in the memory of the mobile phone, and it is very tangled every time it is deleted. Before, you can choose to clean up the chat history in the time range of all time, three months ago and one year ago. Now the time range you can choose is more detailed, and now the option of "custom time" has been added to the filter criteria. By "start date" and "end date", you can clean up the chat records of a certain day, or you can freely choose to clean up the records of a certain time period, so that you can delete them more accurately and greatly improve the convenience.

1905 movie network news Directed by,, starring,,,, starring, and special film release director’s special feature, fully revealing this extreme creative "movie madman". Real-life shooting checks at every level, strives for truth with desperate pursuit, and the lines and expressions fit perfectly … … Every mirror, every person, wherever he goes, pursues the ultimate, and in the delicacy, generate has strong vitality, which stimulates the senses fiercely. As the third part of the "Burning Heart Series", the film Across the Furious Sea also strives to explore love and crime in family of origin more deeply and directly attack the complex three-dimensional human nature. The film will be released nationwide on November 25th, and the pre-sale has been started.

"Madman Director" Cao Baoping greedily created Bo Huang’s evaluation that the director is a wolf in China’s film.

The film Across the Furious Sea, based on a murder case of a girl, cuts open the dark humanity hidden behind two groups of families, and the soul inquiry between good and evil is filled with crime and punishment, love and hate. Today, the film released the director’s special edition, revealing the desperate "madman" side of Cao Baoping’s creation. Cao Baoping reveals "he has an extreme hobby of making", with solid and vivid story text, delicate and true performance emotions and strict and thorough live shooting. Every step is made to be "cruel" to the extreme with the strong vitality of generate, so that the audience can feel the emotional power like a storm.

Every shot is a greedy creative journey for the director. On the shooting set, the director changed into a "movie madman" and strived for perfection everywhere. The "work madman" personally went to the fishing boat for real-life shooting, and seasickness also insisted on the whole process; "Real Madmen" shot for life, Bo Huang, Youhao Zhang and the subway staged a close collision, and Bo Huang ridiculed that "the director is sometimes unreasonable and human"; The "detail madman" has to control the details of the performance to reach every expression. In the face of the powerful actor Bo Huang, the director will also carefully buckle the rhythm of his lines and expressions, laughing that "expressions are also words"; "NG Madman" is always demanding higher standards, with nine NG shots at an altitude of 50 meters, eight shots in the water and three days in the sea, constantly demanding the characters’ hearts, just to fully reflect the despair and suffocation of the characters … … Actor Bo Huang praised the filming operation of the director’s "Crazy Extreme". "Only this greed can make Cao Baoping a wolf in China’s movies. At least ten directors like Cao Baoping can make China’s film genre solid and rich enough."

In addition, the director also revealed in the special edition that the film is by no means a simple revenge film. Although there are intense plots and visually exciting scenes in the film, the film still hopes to explore love and crime in family of origin from the parent-child relationship between the suspect and the victim, trying to dig more complicated human nature possibilities.

Cao Baoping’s extreme enthusiasm infected the actors to go to explore the true nature of human nature in two directions.

Undoubtedly, Cao Baoping is a unique director in China today. As a leading figure in Chinese-language crime movies, his (2008), (2015) and (2016) films are all masterpieces with high marks, which have been sought after by everyone as classics. Because the main actors who directed many films won heavyweight awards at domestic and foreign film festivals, they were even named "the best actor manufacturing machine" by the media.

The "madness and ferocity" created by director Cao Baoping also infects every actor. In the performance, the director will make the actors deeply immersed in the high emotions of the characters, constantly draining the possibility of performance and giving them a great psychological impact. Director Cao Baoping is also very satisfied with the actors’ ultimate performance, saying that "all emotional collisions are crazy to the extreme." Starting from realism, approaching the role to examine its living state, the true nature of human nature emerges in the painful desperate situation. This makes Cao Baoping’s films present a spectacle ecology of coexistence of coldness and ardor, and interaction of drama and plainness, forming its own unique temperament type.

The film Across the Furious Sea is directed and written by Cao Baoping, co-written, starring Bo Huang and Zhou Xun, starring Zu Feng, Youhao Zhang, Zhou Yiran, Yan Bei and Sun Anke, and featuring NI YAN and Wang Xun. It will be released nationwide on November 25th.