Andy Lau, Zhang Yimou and Chen Kaige lead 11 blockbusters! Which one do you want to watch on Mid-Autumn National Day? What listed companies are behind the movie?

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The long holiday begins today, which relaxes the mood, except for the stock market.in lifeThere are more important things. You might as well make an appointment with your family and friends and go to the cinema to enjoy your time.
After experiencing the hot summer file with a new box office record of 20.619 billion yuan, what surprises will the audience get from the Mid-Autumn Festival National Day file?
Eleven films, such as Rock-Solid, Moscow Action, It’s not as if I’m so excited, Ex-4: Early Marriage, Volunteers: Attack by Soldiers, were assembled! It’s the rhythm of "living" in the cinema again. So many movies, which one do you want to see?
01
Rock-solid
Release date: September 28th.
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Among the Mid-Autumn National Day movies, Zhang Yimou, 73, is undoubtedly the brand-new masterpiece "Rock Solid".
"Rock-solid", which lasted for four years and finally met with you, was his first challenge to the theme of urban crime. Before that, he revealed in an interview: "This is an urban, modern and cold style that I have never tried."
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Source: The movie "Rock Solid" official Weibo
According to Zhongxin. com, director Zhang Yimou said at the film conference that he didn’t have many realistic works, but Rock Solid was sharp and powerful, and the shooting process was very special. "From visual style to completion to final filming, it was a rare experience and attempt."
In addition, Zhang Yimou joked in the interview, "If Rock-Solid is released before The Knockout, Yu Hewei will be the first and Zhang Songwen will be the second". When this statement comes out, it will make everyone’s expectations full.
02
Volunteer Army: Attack by Soldiers
Release time: September 28th.
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As the first part of the trilogy "Volunteers", Volunteer Army: Attack with Brave Soldiers tells the story from how to decide to send troops to the first and second battles of Chinese people’s Volunteer Army’s entry into the DPRK. The film will be released nationwide on September 28th, 2023.
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The biggest difference between the trilogy of Volunteers and the previous films on the theme of resisting US aggression and aiding Korea is that it shows this "war of founding the country" in a panoramic and multi-dimensional way.
The story spans three years and completely presents the historical context of the War to Resist US Aggression and Aid Korea. There are more than 200 key figures, including leaders, generals and unknown soldiers. The individual destiny and the times complement each other, showing the audience a magnificent war group image.
03
International Train Robbery’ 93: Operation Moscow
Release date: September 29th.
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Source: The film "Moscow Action" official Weibo
The film "93 International Train Robbery: Moscow Action", co-produced by Han Sanping and Andy Lau and directed by Qiu Litao, reproduces the extremely brutal transnational case and the high-energy hard-core pursuit!
The film gathers Andy Lau, Zhang Hanyu, Huang Xuan, Janice Man and other luxury lineups, presenting the audience with the only violent crime action blockbuster in the National Day file, which will be released on September 29th!
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As the only criminal action blockbuster in the National Day of 2023, the movie "Moscow Action" is strictly made with top-level industrialization standards, with fast and accurate fighting and gun battles, hard-burning and explosive car racing, intense and thrilling firepower, and the audience subverts their imagination, giving them an extremely enjoyable audio-visual feast!
04
Ex-4: Early Marriage
Release date: September 28th.
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In 2017, a "Ex-3: Goodbye to Ex-3" detonated the "ex-emotion" about breaking up and gained 1.9 billion box office. After a lapse of six years, Ex-4: Early Marriage is back again, and the question of "what is love" is carried through to the end. This time, Meng Yun and Yu Fei, the "former" old friends, will face new marriage problems.
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The film tells the story of Meng Yun, who is caught in the "sequela of breakup", while looking for his destiny, thinking about "why do people get married"; On the other hand, Yu Fei started the "marriage cooling-off period", from the involution of couples to frequent problems, and ushered in a new round of love challenges.
05
It doesn’t seem so hot.
Release date: September 28th.
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The only comedy on Mid-Autumn National Day, It’s not as if I have a boiling passion, was written and supervised by Xing Wenxiong, directed by Gao Hu and starring Wei Xiang, Wang Zhi and Yue Liang.
The film tells the story of Wei Guozheng, a conceited coach who pursues "playing to win". He meets a group of players who love basketball but have a negative ability value, and forms a nameless "Benevolence House" basketball team.
pictureIn the daily training that chickens talk to ducks every day, how can coach Wei, who is on the verge of collapse, turn decay into magic and save the basketball team that is on the verge of bankruptcy? Whether they can be together "negative and positive" and achieve a real counterattack will be seen on the field.
06
I am the Return of the Hero of Nezha 2.
Release date: September 29th.
Every holiday is indispensable for children to watch animated films. Among the four animated films to be released this year, I am the Return of the Hero of Nezha 2, Beckon Bear: mission to mars, The Legend of the Little Mermaid’s Sea Monster and Kung Fu King’s Tiger Climbing the Mountain, I am the Return of the Hero of Nezha 2 has received the highest attention.
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The film tells the story of Nezha and the Three Dragons mutually assured destruction after the Chentangguan War. Taiyi real person brought Nezha’s immortal body back to Qianyuan Mountain, waiting for the opportunity to regenerate Nezha to help Jiang Ziya to worship the gods.
At the critical moment of rebirth, Nezha fell into a huge conspiracy carefully arranged by Shen Gongbao and the Dragon King of the East China Sea. Can Nezha break the spell of Shen Gongbao? Can you be a real hero? Nezha’s difficult road to rebirth is about to open, and the battle for the hero’s return is imminent.
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07
Which listed companies are behind the National Day file?
Movies are introduced here. As a financial blogger who spends every day in the stock market, I still want to analyze the listed companies behind these movies.
This year’s National Day, Light, Huayi and Bona will not be absent. Bona produced Chen Kaige’s Volunteer Army: Attack by Soldiers, while Light prepared Zhang Yimou’s Rock-solid. The release dates of the two films are only two days, which is the first time that the two directors have confronted each other in the commercial market. In Huayi’s hand, it is Tian Yusheng’s "Former" series "Former 4: Early Marriage" at the end of the decade.
At present, a total of 7 films have been scheduled for the National Day Mid-Autumn Festival. According to the data of Cat’s Eye Professional Edition, the upper limit of box office predicted by "Rock Solid" and "Previous 4" is 1.78 billion yuan and 2.5 billion yuan respectively, and the box office predicted by "Volunteers" is 1.28 billion yuan to 1.5 billion yuan. At present, the predicted box office of no films exceeds 3 billion yuan, and the total predicted box office of announced films is about 4.4 billion to 6.4 billion yuan.
Looking at the performance in the first half of the year, the light media can be described as steady development.
In the first half of the year, Light Media achieved revenue of 605 million yuan, a year-on-year increase of 3.78%; The net profit of returning to the mother was 203 million yuan, a year-on-year increase of 1.12%.The films mainly invested by Light Media include Deep Sea in the Spring Festival and So Many Years in May 1st. In addition to Deep Sea, Light Media also participated in Manjianghong and Exchange of Life in the Spring Festival of 2023.
However, although "Man Jiang Hong" has a high box office. However, the investment proportion of light is not high, and the income is not as good as the main slide with lower box office. The revenue range of the mainland box office of Light Media, which originated from "Man Jiang Hong", is expected to reach about 100 million, which is lower than the revenue brought by "Deep Sea".
By contrast,Bona Film, which just landed on the A-share market last year, had a hard time.
According to the financial report, the company’s operating income was about 850 million yuan, down 42.31% year-on-year; The net profit attributable to shareholders of listed companies was about-265 million yuan, down 212.22% year-on-year. Bona explained in the financial report that the main reason was that during the reporting period, compared with last year, the company invested in films with different orders of magnitude, and its performance was not as good as that of the same period last year.

thisNational day file,Bona bet on "Volunteers: Attack by Soldiers". By the end of June, the accounts receivable of Bona Film reached 830 million yuan, accounting for 97.65% of the revenue, and the net cash flow generated by operating activities in the same period was only-120 million yuan.

Huayi BrothersAbsentthis yearSummer file.
In the first half of 2023, five films were released by Huayi Brothers: Wandering Earth 2, Rock Tibetan Mastiff: Riding the Wind and Waves, Cosmic Exploration Editorial Department, Love is Beautiful, and Slam Dunk Master. The main films: Rock Tibetan Mastiff: Riding the Wind and Waves and Love is Beautiful were 39.624 million and 14.551 million respectively. At present, the upcoming "Former 4" in the National Day file may become the "life-saving straw" of Huayi Brothers.
According to the financial report, Huayi achieved an operating income of 339 million yuan in the first half of 2023, a year-on-year increase of 59.93%; The net profit loss of returning to the mother was 143 million yuan, which was 192 million yuan in the same period of last year, and the loss was narrowed compared with the same period of last year.

Mid-Autumn Festival should be complete.
I wish you all a high monthly salary and a long income.
Leave this long vacation in the comments section, what do you like best?A movie, and explain the reasons.. The three users who have the highest praise in the comment area will receive a surprise gift carefully prepared by Snowball. (Deadline for activities: Until October 7th.picture)
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Do you still need a structural biologist with AI? Wait for the top experts in Shi Yigong to see it this way.

Recently, Yan Ning, a famous structural biologist, announced that he would resign from Princeton University and set up the Academy of Medical Sciences in Shenzhen. In response to the latest research that she will focus on when she returns to China, she said that the discovery of structural biology is of great significance to the pharmaceutical industry, including the research on the interaction between drugs and hormones, which has more implications for drug development and disease treatment.

Yan Ning said, for example, that through the method of structural biology, scientists saw for the first time that two commonly used drugs used protein as a "scaffold", which directly "side by side" affected the normal function of protein.

Technological change promotes the development of structural biology.

Protein, as the scaffold and main substance of human tissues and organs, plays an important role in human life activities. In the cell, a large number of protein elements form the molecular machines, which performs important molecular processes in the cell through the interaction of protein, including the cell’s response to the external environment and the internal environment, and also forms a signal transduction network system with the interaction of protein as a link.

Structure By studying the three-dimensional structure, dynamic process and biological function of biological macromolecules, biology can provide more details of protein interaction and real-time dynamic process, thus helping scientists to understand molecular mechanism and explore the pathogenesis of diseases related to macromolecular dysfunction.

The development of biology not only contributes to the discovery of drugs, but also affects the research fields of life sciences including biochemistry, cell biology, genetic development, neurobiology, microbiology and pathopharmacology.

The development of science and technology has been promoting the progress of structural biology. In 2017, the Nobel Prize in Chemistry was awarded to cryoelectron microscopy, which can greatly improve the efficiency of analyzing the atomic resolution three-dimensional structure of large protein complexes; Moreover, researchers can freeze biomolecules in motion and visualize their motion process.

This breakthrough has brought a perfect storm to the field of structural biology. In recent years, important breakthroughs have been made in the field of life sciences. The work of China scientists such as Cheng Yifan, Shi Yigong, Yang Maojun and Liu Zhengfeng has also benefited from this technology. They have analyzed the important complex structure of atomic resolution. In addition, the enzyme that produces the protein that leads to Alzheimer’s syndrome was analyzed by cryomicroscope.

In August, 2015, Shi Yigong’s research team published an article in Nature, reporting the three-dimensional electron microscope structure of human γ -secretase with a resolution of 3.4 angstrom, and studying the function of the pathogenic mutant of γ -secretase based on the structure analysis, which provided an important foundation for understanding the working mechanism of γ -secretase and the pathogenesis of Alzheimer’s disease.

In February, 2020, after the outbreak of COVID-19, the research team of West Lake University successfully analyzed the full-length structure of novel coronavirus receptor ACE2 for the first time by using cryo-electron microscopy, which helped the research and development of drugs in COVID-19.

What does AI predict protein folding change?

With the help of artificial intelligence technology, DeepMind, a subsidiary of Google, recently announced 220 million kinds of protein structures predicted by AlphaFold software, which shocked the field of structural biology, because it indicates that artificial intelligence enterprises have begun to "truly hand over the power of Al to scientists all over the world".

Scientists compare the significance of this disruptive breakthrough with the human genome project. In the 1990s, when the Human Genome Project began to take shape, scientists realized that it was not enough to master the base arrangement of genes, but also to know the protein, the product of genes.

Shi Yigong, academician of China Academy of Sciences, structural biologist and president of West Lake University, commented on AlphaFold’s work: "Its accurate prediction of protein structure is the greatest contribution of artificial intelligence to the scientific field, and it is also one of the most important scientific breakthroughs made by mankind in the 21st century."

Shi Yigong once told China Business News: "AlphaFold represents the world’s leading artificial intelligence protein organization prediction system." At the same time, he said, China’s high-tech enterprises are catching up, expecting to bring surprises to the world in the near future.

He also said that the improvement of the accuracy of protein structure prediction will greatly benefit the pharmaceutical industry. "Artificial intelligence prediction of protein structure provides an important foundation for drug design and optimization. The structure of drug target proteins combined with all small molecule drugs can almost be wiped out by AlphaFold. " Shi Yigong said.

In the opinion of some scientists, although AlphaFold’s work is shocking, the accuracy of drug research and development prediction is not enough. Professor Liu Zhijie, executive director of iHuman Institute, Shanghai University of Science and Technology, told the First Financial Reporter: "It has been a long time to predict the protein structure. Now the accuracy of the prediction is definitely getting higher and higher, but it still hasn’t reached the precision of crystal structure."

Liu Zhijie First Financial News told the reporter that the crystal structure is the most accurate, and now artificial intelligence can predict the protein folding with the accuracy of electron microscope and nuclear magnetic resonance. In addition, because there are thousands of structures in protein, the difficulty of analysis is different. "If some protein sequences are similar to the known structure of artificial intelligence, it is easier to predict." Liu Zhijie said.

However, he still believes that with the continuous improvement of the prediction accuracy of protein folding, it will play a more important role in the field of life sciences in the future. "If the current prediction can reach the accuracy of electron microscope, some drugs can already be designed. Drug design is the biggest application field of artificial intelligence protein folding prediction." Said to Liu Zhijie First Financial Reporter.

Others think that with the development of artificial intelligence, there may not be so many structural biologists in the future. "Many researchers who do structural biology are actually more like technical service personnel. The more people there are, the more structures that can be analyzed. Therefore, in essence, a large part of their work depends on manpower. Now with AI, it is true that a large number of people who do structural biology have changed careers." A virus researcher told the First Financial News reporter.

However, for top structural biologists such as Shi Yigong, technology is only a powerful support for the "top brain", which can help them realize more ideas. "Every conscientious biologist should know how to make good use of the structural prediction of artificial intelligence." Shi Yigong said.

Professor Michael Levitt, winner of the Nobel Prize in Chemistry in 2013, told China Business News: "I think many structural biologists are not only doing structural research, but also doing a lot of work on protein function and drug research and development, just like Professor Yan Ning. Artificial intelligence only liberates a part of traditional manpower, but the progress of science still needs to rely on the smartest human brain. I’m afraid that artificial intelligence alone will not work. "

In recent years, a number of AI pharmaceutical companies have also been born in China. In this regard, Ewing Nan, academician of Chinese Academy of Sciences and president of Beijing Institute of Scientific Intelligence, pointed out to the First Financial Reporter: "The emergence of AI for Science research paradigm is an important historical opportunity for scientific and technological innovation, which not only expands the capability boundary of data-driven and physical model-driven models, but also is expected to promote the organic combination of the two, provide theoretical basis for further solving practical problems, and greatly narrow the distance between scientific research and practical application."

Beiqing: Li Tie verbally apologize for the Football Association "I don’t want to add trouble anymore"

Live broadcast November 30th. According to Beiqing report, Li Tie himself recently found Chen Yiyuan, chairman of the Chinese Football Association, profoundly self -review and sincere apology.mean.

For Li Tie’s future, the Chinese Football Association will submit a report to the superior management department. After approval, it will announce the final result through official channels in December.

Li Tie brought the country’s feet this afternoon to the last outdoor training of this closed training at the Taihu Taihu Football Base in Suzhou.Subsequently, the team will take one day on December 1 and be collectively transferred to Shanghai on December 2 to receive "independent observation".Because some Chinese Super League teams have recently come to Shanghai to prepare for the Chinese Super League, some of the national football will directly meet with the club troops, and the national football coaching team will not arrange any collective training in Shanghai.

The People’s Daily praised the national table tennis, but Sun Yingsha, who named the crown, did not mention Wang Manyu, see who is MVP

On November 30th, Beijing time, the World Table Tennis Championships had officially concluded. The final record of the National Table Tennis was to gain 4 gold medals and lost the men’s doubles championship.

Although there were no 5 gold medals, the results of Guoping are still very good, and it has also received praise from the official social media of the People’s Daily. However, Wang Manyu and Fan Zhendong, who played the best winner this time, did not be named. The only one who was named was Sun Yingsha who had lost the women’s singles championship. It turned out that she was the MVP of this year’s national table tennis, although she Did not win the most gold -content award.

《人民日报》亲自开口谈到了国乒这次的情况,并且晒出了九宫格图片,九宫格当中也是有国乒本次出征的大部分主力选手,包括孙颖莎,王曼昱,樊振东,梁靖崑,以及王楚钦和Lin Gaoyuan, Chen Meng and Wang Yidi and others.

They also accompanied: "The Houston World Table Tennis Championships ended in 2021, and the Chinese team ended with four gold results." Then he specifically designed Sun Yingsha: "Sun Yingsha World Table Tennis Championship harvested 2 gold and 1 silver. Each point is every point. Not easy, every player is good, hard, Chinese table tennis, pride for you! "

They recognized Sun Yingsha’s series of contributions, so they mentioned that Sun Yingsha’s two gold and one silver alone, which shows that Sun Yingsha is the real MVP. Wang Manyu did win, and completed the double championship and won the championship of the women’s singles and women’s doubles, but her performance was not as good as Sun Yingsha. Although Sun Yingsha said that the women’s singles won the runner -up, she was in the mixed doubles and her All the women’s double -line operations won the gold medal, and even Sun Yingsha was a third -line operation.

One day before the start of the final, Sun Yingsha even played 4 games in one day, a mixed doubles semi -final and a mixed doubles final, and there were two semi -finals of women’s singles and women’s doubles. Playing 4 games a day and remained full of victory. More importantly, Sun Yingsha defeated the Japanese team’s five giants Zhang Benzhi, Ito Makoto, Hayawa Miyu, Ishikawa Jiachun.

She defeated Hirano Miyu and Ishikawa Jiachun in the 1/4 finals of the Women’s Doubles, and defeated Ito Makoto and Haya Hina in the women’s doubles finals. Facing the Japanese five giants, people played 9 wins and 2 losses. The third -tier operations were better than Wang Manyu. She was the real MVP. Sun Yingsha.

What’s more?

Wang Manyu has only two gold medals, and the mixed doubles competition will go out early, but Sun Yingsha is 2 gold and 1 silver, so the "People’s Daily" will specifically recognize her. She is the real MVP. Only she has received such treatment. Liu Guoliang recognizes her. Normally, this is the treatment of the next Grand Slam and the National Table Tennis Demon King.

This may also be why Liu Guoliang and Li Yan will personally serve as Sun Yingsha’s coaches during this World Table Tennis Championships, find a problem for her, and give her a guest to feed her the ball. On the one hand, it is indeed because Sun Yingsha has no supervisor in charge, and on the other hand, it may be because Sun Yingsha has always been Liu Guoliang’s favorite first love general.